Protein Alignment ppk10 and Scnn1b

DIOPT Version :9

• Sequence 1: NP_001033894.1
• Gene: ppk10 / 3885617
• FlyBaseID: FBgn0065110
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: NP_036780.1
• Gene: Scnn1b / 24767
• RGDID: 3640
• Length: 638
• Species: Rattus norvegicus
• Alignment Length: 610
• Identity: 122/610 - (20%)
• Similarity: 196/610 - (32%)
• Gaps: 237/610 - (38%)

  Fly    20 VLYFNNCCIHGFRYLTDSMLILFE----KFLWLILLIASIYFCIIVCLS---SIDRYYTKSTHIG 77
            |.|.||...||      ...|:.|    |.:|.:|   ::.|..:||..   .|..|.  |..:.
  Rat    27 VWYCNNTNTHG------PKRIICEGPKKKAMWFLL---TLLFACLVCWQWGVFIQTYL--SWEVS 80

  Fly    78 IERNYIFWNTTLPSVTVCPVDRLNITYFADYCRNNGIKGPQRDILWDFLENL-----------AN 131
            :..:..|.....|:||||     |.:.| .|.:   :|...:| |:..:|.:           .|
  Rat    81 VSLSMGFKTMNFPAVTVC-----NSSPF-QYSK---VKHLLKD-LYKLMEAVLDKILAPKSSHTN 135

  Fly   132 ST-YINFQ--NIPQNEQIDQIIEDIGLKPEHYTELIYNLTYDRTYEPN-------------FNER 180
            :| .:||.  |......||:      ..|:|  .::.||..|.....|             ...|
  Rat   136 TTSTLNFTIWNHTPLVLIDE------RNPDH--PVVLNLFGDSHNSSNPAPGSTCNAQGCKVAMR 192

  Fly   181 IRCMDGAM-----FIHVRQVLTEWGL----------------------------CYLGNSKLTEE 212
            :...:|.:     |....|.:|||.:                            |..|    ||.
  Rat   193 LCSANGTVCTFRNFTSATQAVTEWYILQATNIFSQVLPQDLVGMGYAPDRIILACLFG----TEP 253

  Fly   213 YSSRYF--IFGKYPEY-NKYEYE-----------------NIRLPYQVGSFFQKDTQYALLGFKG 257
            .|.|.|  ||  ||:| |.|.:.                 .::|...:|   |:|....|....|
  Rat   254 CSHRNFTPIF--YPDYGNCYIFNWGMTEKALPSANPGTEFGLKLILDIG---QEDYVPFLASTAG 313

  Fly   258 PAIIAFAHSAFEVMKVDSNSDYAYD------GILYD-------------LSTEEITAEDNLEQD- 302
            ..::......:..::  ....||..      |:|.|             ::..:: |..||..|
  Rat   314 ARLMLHEQRTYPFIR--EEGIYAMAGTETSIGVLLDKLQGKGEPYSPCTMNGSDV-AIQNLYSDY 375

  Fly   303 -TTVAMRRCRFPHESNLTHFPFYTRNICQQECRINLAYKICKCIPHFYPNRIANPKPVCDYKTLR 366
             ||.:::.|               .:.|.|:..|:    .|.|..:.||  :...:..|:.:.
  Rat   376 NTTYSIQAC---------------LHSCFQDHMIH----NCSCGHYLYP--LPAGEKYCNNRD-- 417

  Fly   367 SCFPHHASFFLKLYEENGKHENPAICYCEQNCHDSVVTMKSMNPMSGAKQLLGGIGSAVSVKTWP 431
              ||..|..:|.|.....:.|. .:..|:::|:|:...|                  .:|:..||
  Rat   418 --FPDWAYCYLSLQMSVVQRET-CLSMCKESCNDTQYKM------------------TISMADWP 461

  Fly   432 -------------QSR-------LRRQVIFSLTD--------------------LLVSIGGTAGL 456
                         |.|       |.|:.|..|..                    ||.::||..|.
  Rat   462 SEASEDWILHVLSQERDQSSNITLSRKGIVKLNIYFQEFNYRTIEESPANNIVWLLSNLGGQFGF 526

  Fly   457 FLGFSVLGFVE----VIYFFTIRIV 477
            ::|.|||..:|    :|.|..|.::
  Rat   527 WMGGSVLCLIEFGEIIIDFIWITVI 551

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk10	NP_001033894.1	ASC	22..471	CDD:279230	119/600 (20%)
Scnn1b	NP_036780.1	ENaC	21..621	CDD:273304	122/610 (20%)
		deg-1	29..538	CDD:273309	117/593 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	598..620

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820