Protein Alignment ppk10 and Scnn1b

DIOPT Version :9

• Sequence 1: NP_001033894.1
• Gene: ppk10 / 3885617
• FlyBaseID: FBgn0065110
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: NP_001258952.1
• Gene: Scnn1b / 20277
• MGIID: 104696
• Length: 638
• Species: Mus musculus
• Alignment Length: 599
• Identity: 115/599 - (19%)
• Similarity: 193/599 - (32%)
• Gaps: 215/599 - (35%)

  Fly    20 VLYFNNCCIHGFRYLTDSMLILFE----KFLWLILLIASIYFCIIVCLS---SIDRYYTKSTHIG 77
            |.|.||...||      ...|:.|    |.:|.:|   ::.|..:||..   .|..|.  |..:.
Mouse    27 VWYCNNTNTHG------PKRIICEGPKKKAMWFLL---TLLFACLVCWQWGVFIQTYL--SWEVS 80

  Fly    78 IERNYIFWNTTLPSVTVCPVDRLNITYFADYCRNNGIKGPQRDILWDFLENL-------ANST-Y 134
            :..:..|.....|:||||     |.:.| .|.:...:.....:::...||.:       :|:| .
Mouse    81 VSLSMGFKTMNFPAVTVC-----NSSPF-QYSKVKHLLKDLDELMEAVLEKILAPEASHSNTTRT 139

  Fly   135 INFQ--NIPQNEQIDQIIEDIGLKPEHYTELIYNLTYDRTYEPN-------------FNERIRCM 184
            :||.  |......||:      ..|:|  .::.||..|.....|             ...|:...
Mouse   140 LNFTIWNHTPLVLIDE------RNPDH--PVVLNLFGDSHNSSNPAPGSTCNAQGCKVAMRLCSA 196

  Fly   185 DGAM-----FIHVRQVLTEWGL----------------------------CYLGNSKLTEEYSSR 216
            :|.:     |....|.:|||.:                            |..|    ||..|.|
Mouse   197 NGTVCTLRNFTSATQAVTEWYILQATNIFSQVLPQDLVGMGYAPDRIILACLFG----TEPCSHR 257

  Fly   217 YF--IFGKYPEY-NKYEYE-----------------NIRLPYQVGSFFQKDTQYALLGFKGPAII 261
            .|  ||  ||:| |.|.:.                 .::|...:|   |:|....|....|..::
Mouse   258 NFTPIF--YPDYGNCYIFNWGMTEETLPSANPGTEFGLKLILDIG---QEDYVPFLASTAGARLM 317

  Fly   262 AFAHSAFEVMKVDSNSDYAYDGILYDLSTEEIT---AEDNLEQ-----------DTTVAMRRCRF 312
            ......:..::.:.         :|.::..|.:   ..|.|::           .:.||::....
Mouse   318 LHEQRTYPFIREEG---------IYAMAGTETSIGVLVDKLQRKGEPYSPCTMNGSDVAIKNLYS 373

  Fly   313 PHESNLTHFPFYTRNICQQECRINLAYKICKCIPHFYPNRIANPKPVCDYKTLRSCFPHHASFFL 377
            .:.:.      |:...|...|..:...:.|.|..:.||  :...:..|:.:.    ||..|..:|
Mouse   374 VYNTT------YSIQACLHSCFQDHMIRNCSCGHYLYP--LPEGEKYCNNRD----FPDWAYCYL 426

  Fly   378 KLYEENGKHENPAICYCEQNCHDSVVTMKSMNPMSGAKQLLGGIGSAVSVKTWP----------- 431
            .|.....:.|. .:..|:::|:|:...|                  .:|:..||
Mouse   427 NLQMSVTQRET-CLSMCKESCNDTQYKM------------------TISMADWPSEASEDWILHV 472

  Fly   432 --QSR-------LRRQVIFSLTD--------------------LLVSIGGTAGLFLGFSVLGFVE 467
              |.|       |.|:.|..|..                    ||.::||..|.::|.|||..:|
Mouse   473 LSQERDQSSNITLSRKGIVKLNIYFQEFNYRTIEESPANNIVWLLSNLGGQFGFWMGGSVLCLIE 537

  Fly   468 ----VIYFFTIRIV 477
                :|.|..|.|:
Mouse   538 FGEIIIDFIWITII 551

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk10	NP_001033894.1	ASC	22..471	CDD:279230	111/589 (19%)
Scnn1b	NP_001258952.1	ENaC	21..621	CDD:273304	115/599 (19%)
		deg-1	29..538	CDD:273309	109/582 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	594..620

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820