Protein Alignment ppk10 and Scnn1a

DIOPT Version :9

• Sequence 1: NP_001033894.1
• Gene: ppk10 / 3885617
• FlyBaseID: FBgn0065110
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: NP_035454.2
• Gene: Scnn1a / 20276
• MGIID: 101782
• Length: 700
• Species: Mus musculus
• Alignment Length: 626
• Identity: 123/626 - (19%)
• Similarity: 195/626 - (31%)
• Gaps: 260/626 - (41%)

  Fly    19 FVLYFNNCCIHGFRYLTDSMLILFEKFLWLILLIASI-----YFCIIVCLSSIDRYYTKSTHIGI 78
            |..:.||..|||...|..|.....:...|.:|.:.:.     .|.::     .:.|::....:.|
Mouse    85 FQFFCNNTTIHGAIRLVCSKHNRMKTAFWAVLWLCTFGMMYWQFALL-----FEEYFSYPVSLNI 144

  Fly    79 ERN---YIFWNTTLPSVTVCPVDRLNITYFADYCRNNGIKGPQRDILWDFLENLANSTYINFQNI 140
            ..|   .:|     |:||||.::....|                    :..|:|
Mouse   145 NLNSDKLVF-----PAVTVCTLNPYRYT--------------------EIKEDL----------- 173

  Fly   141 PQNEQIDQIIEDIGLKPEHYTELIYNL-TYDRTYEPNFNER---IRCMDGAMFIHVRQVLT---- 197
               |::|:|.|          :.:::| .|:.:|......|   .|.:.||:...::::.|
Mouse   174 ---EELDRITE----------QTLFDLYKYNSSYTRQAGGRRRSTRDLRGALPHPLQRLRTPPPP 225

  Fly   198 -----------------------EW----GLCYLGNSK-LTEEYSSRYFIFGKYPEYNKYEYENI 234
                                   :|    .||....|. ..:.|||.   .....|:.::.|.||
Mouse   226 NPARSARSASSSVRDNNPQVDRKDWKIGFQLCNQNKSDCFYQTYSSG---VDAVREWYRFHYINI 287

  Fly   235 --RLPYQVGSFFQKDTQYAL----LGF--------KGPAIIA----FAHSAFEVMKVDSNSDYA- 280
              |||         ||..||    ||.        :.|...|    |.|..:......:|.:.:
Mouse   288 LSRLP---------DTSPALEEEALGSFIFTCRFNQAPCNQANYSQFHHPMYGNCYTFNNKNNSN 343

  Fly   281 ---------YDGILYDLSTEE----------------ITAED----------NLEQ--DTTVAMR 308
                     .:|:...|.||:                :..:|          |:..  :|:::||
Mouse   344 LWMSSMPGVNNGLSLTLRTEQNDFIPLLSTVTGARVMVHGQDEPAFMDDGGFNVRPGVETSISMR 408

  Fly   309 R------------CRFPHESNLTHFPF-------YTRNICQQECRINLAYKICKCIPHFYPNRIA 354
            :            |    ..|.:..|.       ||:.:|...|......|.|.|...|||
Mouse   409 KEALDSLGGNYGDC----TENGSDVPVKNLYPSKYTQQVCIHSCFQENMIKKCGCAYIFYP---- 465

  Fly   355 NPKPV--CDYKTLRS---C-FPHHASFFLKLYEENGKHENPAICY--CEQNCHDSVVTMKSMNPM 411
            .||.|  |||....|   | :...|:|.|   :..|       |:  |.:.|  ||...|
Mouse   466 KPKGVEFCDYLKQSSWGYCYYKLQAAFSL---DSLG-------CFSKCRKPC--SVTNYK----- 513

  Fly   412 SGAKQLLGGIGSAVSVKT--WPQSRLRRQ----------------VIF--------------SLT 444
                 |..|.....|||:  |....|..|                :.|              ::.
Mouse   514 -----LSAGYSRWPSVKSQDWIFEMLSLQNNYTINNKRNGVAKLNIFFKELNYKTNSESPSVTMV 573

  Fly   445 DLLVSIGGTAGLFLGFSVLGFVEVIYFFTIRIVFQILGYTL 485
            .||.::|....|:.|.|||..||:     ..::|.:|..||
Mouse   574 SLLSNLGSQWSLWFGSSVLSVVEM-----AELIFDLLVITL 609

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk10	NP_001033894.1	ASC	22..471	CDD:279230	118/607 (19%)
Scnn1a	NP_035454.2	ENaC	80..677	CDD:273304	123/626 (20%)
		deg-1	88..600	CDD:273309	118/612 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820