Protein Alignment ppk10 and Asic3

DIOPT Version :10

• Sequence 1: NP_001033894.1
• Gene: ppk10 / 3885617
• FlyBaseID: FBgn0065110
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: XP_006535700.1
• Gene: Asic3 / 171209
• MGIID: 2159339
• Length: 563
• Species: Mus musculus
• Alignment Length: 582
• Identity: 104/582 - (17%)
• Similarity: 180/582 - (30%)
• Gaps: 217/582 - (37%)

  Fly    21 LYFNNCCIHGFRYLTDSMLILFEKFLW---LILLIASIYFCIIVCLSSIDRYYTKSTHIGIERNY 82
            ::.|:|.:||..::.....:...:.||   ::|.:|:..:.:...:.....::.|:|....|.:.
Mouse    20 VFANSCTMHGLGHIFGPGGLTLRRGLWATAVLLSLAAFLYQVAERVRYYGEFHHKTTLDERESHQ 84

  Fly    83 IFWNTTLPSVTVC---PVDRLNITYFADYCRNNGIKGPQRDILWD-----FLENLANSTYI---- 135
            :    |.|:||:|   |:.|..:|              ..|:.|.     .|:...::.|:
Mouse    85 L----TFPAVTLCNINPLRRSRLT--------------PNDLHWAGTALLGLDPAEHAAYLRALG 131

  Fly   136 ------NFQNIPQNE------QIDQIIEDIGLK---------PEHYTELIYNLTYDRTYEPNFNE 179
                  .|...|..:      :....:||:.|.         ||::|
Mouse   132 QPPAPPGFMPSPTFDMAQLYARAGHSLEDMLLDCRYRGQPCGPENFT------------------ 178

  Fly   180 RIRCMDGAMFIHVRQVLTEWGLCYLGNS------KLT------------------EEYSSRYFIF 220
                          .:.|..|.||..||      .||                  |||
Mouse   179 --------------VIFTRMGQCYTFNSGAQGAELLTTPKGGAGNGLEIMLDVQQEEY------- 222

  Fly   221 GKYPEYNKYEYENIRLPYQVGSFFQKDTQYALLGFKGPAI------IAFAHSAFEVMKVDSNSDY 279
              .|.:...|    ..|::||...|...|.     :.|||      .|..|..|...:....|
Mouse   223 --LPIWKDME----ETPFEVGIRVQIHGQE-----EPPAIDQLGFGAAPGHQTFVSCQQQQLS-- 274

  Fly   280 AYDGIL----YDLSTEEITAEDNLEQDTTVAMRRCRFPHESNLTHFPFYTRNICQQECRINLAYK 340
                .|    .|.:|..:..:.:.|....:..     |..|     |.|:...|:..|......:
Mouse   275 ----FLPPPWGDCNTASVDPDFDPEPSDPLGS-----PSSS-----PPYSLIGCRLACESRYVAR 325

  Fly   341 ICKCIPHFYPNRIANPKPVCDYKTLRSC--------------FPHHAS----------FFLKLYE 381
            .|.|.....|..    .|||..:..:.|              .|.|:.          .||.|
Mouse   326 KCGCRMMHMPGN----SPVCSPQQYKDCASPALGKAHLFSLPVPIHSDIDHNPLGQVLLFLAL-- 384

  Fly   382 ENGKHENPA-------ICYCEQNC----HDSVVTMKSMNPMSGAKQLLGGIGSA----------- 424
                  .||       .|.|...|    :...::|..:...:.|:.|......:
Mouse   385 ------RPADAMLRKDTCVCPNPCATTRYAKELSMVRIPSRASARYLARKYNRSETYITENVLVL 443

  Fly   425 -VSVKTWPQSRLRRQVIFSLTDLLVSIGGTAGLFLGFSVLGFVEVIYFFTIRIVFQ--ILGY 483
             :..:......:.::..:.:::||..|||..|||:|.|:|..:|::.:  :..|||  :|||
Mouse   444 DIFFEALNYEAVEQKAAYEVSELLGDIGGQMGLFIGASLLTILEILDY--LCEVFQDRVLGY 503

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk10	NP_001033894.1	ASC	22..471	CDD:459966	98/565 (17%)
Asic3	XP_006535700.1	ENaC	21..546	CDD:273304	104/581 (18%)