Protein Alignment ppk10 and asic4

DIOPT Version :10

• Sequence 1: NP_001033894.1
• Gene: ppk10 / 3885617
• FlyBaseID: FBgn0065110
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: XP_031749131.1
• Gene: asic4 / 100486325
• XenbaseID: XB-GENE-940165
• Length: 535
• Species: Xenopus tropicalis
• Alignment Length: 502
• Identity: 93/502 - (18%)
• Similarity: 169/502 - (33%)
• Gaps: 142/502 - (28%)

  Fly    28 IHGFRYLTDSMLILFEKFLWLILLIASIYFCIIVCLSSIDRYYTKSTHIGIERNYIFWNTTLPSV 92
            :||.|::..:..:..::.||.:..:||:.| .:..::....||.:..|:......:......|::
 Frog    50 LHGLRHIFQTGRLGIKQSLWALAFLASLLF-FLYQVAKCALYYLEHPHVTAVDEEVMGEMIFPAI 113

  Fly    93 TVCPVDRLNITYFADYCRNNGIKGPQRDILWDFLENLANSTYINFQNIPQNEQIDQIIED----- 152
            |:|.::|.         |::.:..|.       :.:|||.|.:..::...:...|.:.:|
 Frog   114 TICNINRF---------RHSALTDPD-------IYHLANLTGLPPKDREGHRDSDLMYDDPDMLD 162

  Fly   153 -IGLKPEHYTELI--YNLTYDRTYEPNFNERIRCMDGAMFIHVRQVLTEWGLCYLGNSKLTEEYS 214
             :........|::  .|.:.|.....||:               .|.|.:|.||..|:.......
 Frog   163 IVNRTGHQLAEMLKSCNFSGDSCSAQNFS---------------VVFTRYGKCYTFNADKKHPKV 212

  Fly   215 SRYFIFGK----------------YPEYNKYEYE-NIRLPYQVGSFFQKDTQYA-LLGF-KGPAI 260
            ||....|.                :.|.|:..:| .||:  |:.|  |.:..|. .:|| ..|..
 Frog   213 SRQGGMGNGLEIMLDIQQEEYLPIWRETNETSFEAGIRV--QIHS--QDEPPYIHQMGFGVSPGF 273

  Fly   261 IAFAHSAFEVMKVDSNSDYAYDGILYDLSTEEITAEDNLEQDTTVAMR---RCR--FPHESNLTH 320
            ..|....                                ||..|...:   .||  .|.|..|:.
 Frog   274 QTFVSCQ--------------------------------EQRMTYLPQPWGNCRSSIPGEEFLSG 306

  Fly   321 FPFYTRNICQQECRINLAYKICKC-IPHFYPNRIANPKPVCDYKTLRSCFPHHASFFLKLYEENG 384
            :..|:.:.|:.:|......:.|.| :.|...|     :.:|. ..:..|..|        ..:|.
 Frog   307 YSTYSISACRLQCEKEAVIRKCACRMVHMPGN-----ETICS-PVMYMCADH--------ILDNM 357

  Fly   385 KHENPAICYCEQNC----HDSVVTMKSMNPMSGAKQL-----------------LGGIGSAVSVK 428
            ..:....|.|...|    :...::|..:.....|:.|                 |.....|::.:
 Frog   358 VEDTSEKCSCPTPCNLTRYSKEISMVRIPNKGSARYLARKYNKNETYIRENFLVLDIFFEALNYE 422

  Fly   429 TWPQSRLRRQVIFSLTDLLVSIGGTAGLFLGFSVLGFVEVI-YFFTI 474
            |..|.:     .:.|..||..|||..|||:|.|.|..:|:: |.:.:
 Frog   423 TIEQKK-----AYDLPSLLGDIGGQMGLFIGASFLTILEILDYMYEV 464

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk10	NP_001033894.1	ASC	22..471	CDD:459966	92/497 (19%)
asic4	XP_031749131.1	ENaC	39..514	CDD:273304	93/502 (19%)