Protein Alignment ppk16 and SCNN1B

DIOPT Version :9

• Sequence 1: NP_001334673.1
• Gene: ppk16 / 3885612
• FlyBaseID: FBgn0065108
• Length: 531
• Species: Drosophila melanogaster
• Sequence 2: XP_016879014.1
• Gene: SCNN1B / 6338
• HGNCID: 10600
• Length: 659
• Species: Homo sapiens
• Alignment Length: 597
• Identity: 129/597 - (21%)
• Similarity: 200/597 - (33%)
• Gaps: 196/597 - (32%)

  Fly    41 PQHRFRQIGEWFTENMRNYCQTTSLHGFSYITRQDISRHERWFWLVVVILAIITSIVLVVVSWYW 105
            |.:.::::..|       ||..|:.||...|..:...:...||.|.::..|:        |.|.|
Human    37 PGYTYKELLVW-------YCDNTNTHGPKRIICEGPKKKAMWFLLTLLFAAL--------VCWQW 86

  Fly   106 SQETPT-----VTVIESSHFPTWNIPFPAVTICNFN--KISKSKAL---------SLLDQMQVP- 153
            .....|     |:|..|..|.|  :.||||||||.:  |.||.|.|         ::|:::..|
Human    87 GIFIRTYLSWEVSVSLSVGFKT--MDFPAVTICNASPFKYSKIKHLLKDLDELMEAVLERILAPE 149

  Fly   154 ---VGINRSELHNLFNLTLLPVDTMISNDSLQKYDRILSLNNLTLNRLTQQLSPDCIEMISSCIW 215
               ....|:...:::|.|.|    ::.::....:..:|.|.....|.||.          ||...
Human   150 LSHANATRNLNFSIWNHTPL----VLIDERNPHHPMVLDLFGDNHNGLTS----------SSASE 200

  Fly   216 KGINTRCESLFQRIDTMEGQCCTFNYFGGISNNFPE-------KIAYQVPKRP------------ 261
            |..|.....:..|:.::....|||..|...:....|       .|..|||::.
Human   201 KICNAHGCKMAMRLCSLNRTQCTFRNFTSATQALTEWYILQATNIFAQVPQQELVEMSYPGEQMI 265

  Fly   262 -----------YR-VTGCGYP-------------------------TGLSVLLNPMISDYYGTFF 289
                       || .|...||                         .||.::|:....||.....
Human   266 LACLFGAEPCNYRNFTSIFYPHYGNCYIFNWGMTEKALPSANPGTEFGLKLILDIGQEDYVPFLA 330

  Fly   290 SGFGFRLLLHDAYNFPDENSETKVVTTTRESFVRINPESTYA-----------TNDIRRMDLSLR 343
            |..|.||:||:..::|               |:|  .|..||           .:.::||.....
Human   331 STAGVRLMLHEQRSYP---------------FIR--DEGIYAMSGTETSIGVLVDKLQRMGEPYS 378

  Fly   344 NC-LFGSEMTMHGL-----RRYSFINCMFECRVRMTVDLCGCLPPYVYNNGSY--------KVCG 394
            .| :.|||:.:...     ..||...|:..|.....:..|.|        |.|        |.|
Human   379 PCTVNGSEVPVQNFYSDYNTTYSIQACLRSCFQDHMIRNCNC--------GHYLYPLPRGEKYC- 434

  Fly   395 VLQTNCIIHSKRLF---SHALANLNFSLSIVRETDSFPC--GCLPDCQSNHY---------VSES 445
                     :.|.|   :|..::|..|:: .|||    |  .|...|....|         .||:
Human   435 ---------NNRDFPDWAHCYSDLQMSVA-QRET----CIGMCKESCNDTQYKMTISMADWPSEA 485

  Fly   446 TTGRLDISYFANRPTFNNAT----DRILLHVFFSDLMSTRYRT---DIFQNWLSALASFGGLLGL 503
            :...:.......|....|.|    ..:.|:::|.:.   .|||   ....|.:..|::.||..|.
Human   486 SEDWIFHVLSQERDQSTNITLSRKGIVKLNIYFQEF---NYRTIEESAANNIVWLLSNLGGQFGF 547

  Fly   504 IMGFSIVTAFEF 515
            .||.|::...||
Human   548 WMGGSVLCLIEF 559

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165152145
Domainoid	1	1.000	84	1.000	Domainoid score	I8228
eggNOG	1	0.900	-	-		E1_KOG4294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	88	1.000	Inparanoid score	I5132
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100105
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X60
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	7	6.690