Protein Alignment ppk16 and ASIC4

DIOPT Version :9

• Sequence 1: NP_001334673.1
• Gene: ppk16 / 3885612
• FlyBaseID: FBgn0065108
• Length: 531
• Species: Drosophila melanogaster
• Sequence 2: NP_061144.4
• Gene: ASIC4 / 55515
• HGNCID: 21263
• Length: 539
• Species: Homo sapiens
• Alignment Length: 512
• Identity: 115/512 - (22%)
• Similarity: 176/512 - (34%)
• Gaps: 134/512 - (26%)

  Fly    55 NMRNYCQTTSLHGFSYITRQDISRHERWFWLVVVILAIITSIVLV------VVSWYWSQETPTVT 113
            ::..:..|::|||.............|..|    .||::||:...      :...|.::  |.:.
Human    41 DLATFASTSTLHGLGRACGPGPHGLRRTLW----ALALLTSLAAFLYQAAGLARGYLTR--PHLV 99

  Fly   114 VIESSHFPTWNIP---FPAVTICNFNKISKSKALSLLDQMQVPVGINRSELHNLFNLTLLP---- 171
            .::    |....|   |||||:||.|:...|             .::.:::.:|.|||.||
Human   100 AMD----PAAPAPVAGFPAVTLCNINRFRHS-------------ALSDADIFHLANLTGLPPKDR 147

  Fly   172 ---------------VDTMISNDSLQKYDRILSLNNLTLNRLTQQLSPDCIEMISSCIWKGINTR 221
                           ||                    .|||...||:    :|:.||.:.|  ..
Human   148 DGHRAAGLRYPEPDMVD--------------------ILNRTGHQLA----DMLKSCNFSG--HH 186

  Fly   222 CE-SLFQRIDTMEGQCCTFNYFGGISNNFPEKIAYQVPKRPYRVTGCGYPTGLSVLLN------- 278
            |. |.|..:.|..|:|.|||             |......|.|..|.|  :||.::|:
Human   187 CSASNFSVVYTRYGKCYTFN-------------ADPRSSLPSRAGGMG--SGLEIMLDIQQEEYL 236

  Fly   279 PMISDYYGTFFSGFGFRLLLHDAYNFPDENSETKVVTTTRESFVRINPES-TYATNDIRRMDLSL 342
            |:..:...|.|.. |.|:.:|.....|..:.....|:...::||....:. ||       :....
Human   237 PIWRETNETSFEA-GIRVQIHSQEEPPYIHQLGFGVSPGFQTFVSCQEQRLTY-------LPQPW 293

  Fly   343 RNCLFGSEM---TMHGLRRYSFINCMFECRVRMTVDLCGCLPPYVYNNGSYKVCGVLQTNCIIHS 404
            .||...||:   .:.|...||...|...|.....:..|.|  ..|:..|:..:|   ..|..|..
Human   294 GNCRAESELREPELQGYSAYSVSACRLRCEKEAVLQRCHC--RMVHMPGNETIC---PPNIYIEC 353

  Fly   405 KRLFSHALANLNFSLSIVRETDSFPCGCLPDCQSNHYVSESTTGRL----DISYFANRPTFNNAT 465
            .   .|.|.:|...       ...||.|...|....|..|.:..|:    ...|.|.:...|...
Human   354 A---DHTLDSLGGG-------PEGPCFCPTPCNLTRYGKEISMVRIPNRGSARYLARKYNRNETY 408

  Fly   466 DR---ILLHVFFSDLMSTRYRTDIFQNWLSALASFGGLLGLIMGFSIVTAFEFIYFL 519
            .|   ::|.|||..|.|............:.|...||.:||.:|.||:|..|.:.::
Human   409 IRENFLVLDVFFEALTSEAMEQRAAYGLSALLGDLGGQMGLFIGASILTLLEILDYI 465

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk16	NP_001334673.1	None
ASIC4	NP_061144.4	ASC	40..488	CDD:413546	115/512 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165152199
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100105
Panther	1	1.100	-	-	O	PTHR11690
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X60
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.740