Protein Alignment ppk16 and asic2

DIOPT Version :10

• Sequence 1: NP_001334673.1
• Gene: ppk16 / 3885612
• FlyBaseID: FBgn0065108
• Length: 531
• Species: Drosophila melanogaster
• Sequence 2: XP_005164179.1
• Gene: asic2 / 407669
• ZFINID: ZDB-GENE-040513-4
• Length: 564
• Species: Danio rerio
• Alignment Length: 545
• Identity: 132/545 - (24%)
• Similarity: 193/545 - (35%)
• Gaps: 170/545 - (31%)

  Fly    63 TSLHGFSYITRQDISRHERWFWLVVVILAIITSIVLVVVSW------YWSQETPTVTVIESSHFP 121
            |.|||..:|.....|...|.||::    |..|.:.| ::||      :| ...||.|.:.:.
Zfish    71 TRLHGLRHICSPSNSLSRRAFWMI----AFCTCLGL-LLSWSSNRLLHW-LAFPTHTRVHTE--- 126

  Fly   122 TW--NIPFPAVTICNFNKISKSKALSLLDQMQVPV---GINRSELH--------NLFNLTLLPVD 173
             |  .:.||.|||||.|                ||   .:.:|:|:        .|.|.|..|:.
Zfish   127 -WAKELAFPTVTICNNN----------------PVRLYHLTKSDLYFAGHWLGLLLANRTARPLV 174

  Fly   174 TMISNDSLQKYDRILSLNNLTL-------------NRLTQQLSPDCIEMISSCIWKGINTRCESL 225
            ..:..|..:.:...||...|.|             :||..||.    :|:.:|.::|......:
Zfish   175 LDLLQDDRRGWFSKLSDFRLFLPPRRFEGTSLEFMDRLGHQLE----DMLLACKYRGEPCGAHN- 234

  Fly   226 FQRIDTMEGQCCTFNYFGGISNNFPEKIAYQVPKRPYRVTGCGYPTGLSVLLNPMISDY---YG- 286
            |..:.|..|:|..||             |.:..|........|...||.::|:....:|   :|
Zfish   235 FSTVFTRYGKCYMFN-------------AAEEGKTLRTTMKGGTGNGLEIMLDIQQDEYLPVWGE 286

  Fly   287 ---TFFSGFGFRLLLHDAYNFPDENSETKVVTTTRESFVRINPESTYATNDIRRMDL-------- 340
               |.|.. |.|:.:|.....|..:.....|....::||        ||.:.|...|
Zfish   287 TEETAFEA-GVRVQIHSQAEPPFVHELGFGVAPGFQTFV--------ATQEQRLTYLPPPWGECV 342

  Fly   341 --SLRNCLFGSEMTMHGLRRYSFINCMFECRVRMTVDLCGCLPPYVYNNG------SYKVC---- 393
              :|.:.||         :.||...|..||..|..|:.|.|...|:..:.      .||.|
Zfish   343 SRALDSGLF---------QVYSVSACRIECETRYIVENCNCRMVYMPGDSPYCTPEQYKDCAEPA 398

  Fly   394 -----GVLQTNCIIHSKRLFSHALANLNFSLSIVRETDSFPCGCLPDCQSNHYVSESTTGRLDIS 453
                 .|..||||..|    ...:...|..||:|:         :|...|..|:.:.
Zfish   399 LAALSAVEGTNCICRS----PCNMTRYNKELSMVK---------IPSKTSARYLEKK-------- 442

  Fly   454 YFANRPTFNNA----TDRIL-LHVFFSDLMSTRYRTDIFQ----NWLSALASFGGLLGLIMGFSI 509
                   ||.:    ||.|| |.|||..|   .|.| |.|    .....|...||.:||.:|.||
Zfish   443 -------FNRSEKYITDNILVLDVFFEAL---NYET-IEQKKAYEVAGLLGDIGGQMGLFIGASI 496

  Fly   510 VT---AFEFIYFLTFRPVFNYINRE 531
            :|   .|::.|.:....:.:.:|||
Zfish   497 LTLLELFDYAYEVVKERLLDLLNRE 521

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk16	NP_001334673.1	ASC	59..518	CDD:459966	128/530 (24%)
asic2	XP_005164179.1	ENaC	71..538	CDD:273304	132/545 (24%)