Protein Alignment ppk16 and ASIC2

DIOPT Version :9

• Sequence 1: NP_001334673.1
• Gene: ppk16 / 3885612
• FlyBaseID: FBgn0065108
• Length: 531
• Species: Drosophila melanogaster
• Sequence 2: NP_899233.1
• Gene: ASIC2 / 40
• HGNCID: 99
• Length: 563
• Species: Homo sapiens
• Alignment Length: 537
• Identity: 129/537 - (24%)
• Similarity: 198/537 - (36%)
• Gaps: 152/537 - (28%)

  Fly    65 LHGFSYI----TRQDISRHERWFWLVVVILAIITSIVLVVVSW------YWSQETPTVTVIESSH 119
            |||..::    |....|...|..|    :||..||..| ::||      || ...|:.|.:...
Human    66 LHGLRHMCAGRTAAGGSFQRRALW----VLAFCTSFGL-LLSWSSNRLLYW-LSFPSHTRVHRE- 123

  Fly   120 FPTWN--IPFPAVTICN-----FNKISKSKA------LSLLDQMQVPVGINRSELHNLFNLTLLP 171
               |:  :||||||:||     |.::||...      |.||                |.|.|..|
Human   124 ---WSRQLPFPAVTVCNNNPLRFPRLSKGDLYYAGHWLGLL----------------LPNRTARP 169

  Fly   172 V--DTMISNDSLQKYDRILS-------------LNNLTLNRLTQQLSPDCIEMISSCIWKGINTR 221
            :  :.:..::..:::.|.|:             ::...::||..||.    :|:.||.::|  ..
Human   170 LVSELLRGDEPRRQWFRKLADFRLFLPPRHFEGISAAFMDRLGHQLE----DMLLSCKYRG--EL 228

  Fly   222 C-ESLFQRIDTMEGQCCTFNYFGGISNNFPEKIAYQVPKRPYRVT---GCGYPTGLSVLLNPMIS 282
            | ...|..:.|..|:|..||  .|...            :|...|   |.|  .||.::|:....
Human   229 CGPHNFSSVFTKYGKCYMFN--SGEDG------------KPLLTTVKGGTG--NGLEIMLDIQQD 277

  Fly   283 DY---YG----TFFSGFGFRLLLHDAYNFPDENSETKVVTTTRESFVRINP--ESTYATNDIRRM 338
            :|   :|    |.|.. |.::.:|       ..||...:   :|....:.|  ::..||.:.|..
Human   278 EYLPIWGETEETTFEA-GVKVQIH-------SQSEPPFI---QELGFGVAPGFQTFVATQEQRLT 331

  Fly   339 DL--SLRNCLFGSEMTMHGLRRYSFINCMFECRVRMTVDLCGCLPPYVYNNGSYKVCGVLQ-TNC 400
            .|  ....|. .|||.:.....||...|..:|..|..|:.|.|  ..|:..|....|...| ..|
Human   332 YLPPPWGECR-SSEMGLDFFPVYSITACRIDCETRYIVENCNC--RMVHMPGDAPFCTPEQHKEC 393

  Fly   401 IIHSKRLFSHALANLNFSLSIVRETDSFPCGCLPDCQSNHYVSE----STTGRLDISYFANRPTF 461
                          ...:|.::.|.||..|.|...|....|..|    ....:....|...:  |
Human   394 --------------AEPALGLLAEKDSNYCLCRTPCNLTRYNKELSMVKIPSKTSAKYLEKK--F 442

  Fly   462 NNA----TDRIL-LHVFFSDLMSTRYRTDIFQ----NWLSALASFGGLLGLIMGFSIVT---AFE 514
            |.:    ::.|| |.:||..|   .|.| |.|    ...:.|...||.:||.:|.||:|   .|:
Human   443 NKSEKYISENILVLDIFFEAL---NYET-IEQKKAYEVAALLGDIGGQMGLFIGASILTILELFD 503

  Fly   515 FIYFLTFRPVFNYINRE 531
            :||.|....:.:.:.:|
Human   504 YIYELIKEKLLDLLGKE 520

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk16	NP_001334673.1	None
ASIC2	NP_899233.1	ENaC	64..547	CDD:273304	129/537 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165152155
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100105
Panther	1	1.100	-	-	O	PTHR11690
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X60
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.740