DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ppk16 and Asic3

DIOPT Version :9

Sequence 1:	NP_001334673.1	Gene:	ppk16 / 3885612	FlyBaseID:	FBgn0065108	Length:	531	Species:	Drosophila melanogaster
Sequence 2:	XP_038963092.1	Gene:	Asic3 / 286920	RGDID:	708578	Length:	564	Species:	Rattus norvegicus

Alignment Length:	525	Identity:	115/525 - (21%)
Similarity:	175/525 - (33%)	Gaps:	139/525 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    55 NMRNYCQTTSLHGFSYITRQDISRHERWFWLVVVILAIITSIVLVV--VSWYWSQETPTVTVIES 117
            ::|.:..:.::||..:|.........|..|...|:|::...:..|.  |.:|......|......
  Rat    17 DIRVFASSCTMHGLGHIFGPGGLTLRRGLWATAVLLSLAAFLYQVAERVRYYGEFHHKTTLDERE 81

  Fly   118 SHFPTWNIPFPAVTICNFNKISKSKA-----------------------LSLLDQMQVPVGINRS 159
            ||    .:.|||||:||.|.:.:|:.                       |..|.|...|.|
  Rat    82 SH----QLTFPAVTLCNINPLRRSRLTPNDLHWAGTALLGLDPAEHAAYLRALGQPPAPPG---- 138

  Fly   160 ELHNLFNLTLLPVDTMISNDSLQKYDRI-LSLNNLTLNRLTQQLSPDCIEMISSCIWKGINTRCE 223
                     .:|..|.   |..|.|.|. .||.                :|:..|.::|.....|
  Rat   139 ---------FMPSPTF---DMAQLYARAGHSLE----------------DMLLDCRYRGQPCGPE 175

  Fly   224 SLFQRIDTMEGQCCTFNYFGGISNNFPEKIAYQVPKRPYRVTGCGYPTGLSVLLN-------PMI 281
            : |..|.|..|||.|||     |.....:: ...||     .|.|  .||.::|:       |:.
  Rat   176 N-FTVIFTRMGQCYTFN-----SGAHGAEL-LTTPK-----GGAG--NGLEIMLDVQQEEYLPIW 226

  Fly   282 SDYYGTFFSGFGFRLLLH--------DAYNFPDENSETKVVTTTRESFVRINP---ESTYATNDI 335
            .|...|.|. .|.|:.:|        |...|.........|:..::....:.|   :...|:.|.
  Rat   227 KDMEETPFE-VGIRVQIHSQDEPPAIDQLGFGAAPGHQTFVSCQQQQLSFLPPPWGDCNTASLDP 290

  Fly   336 RRMDLSLRNCLFGSEMTMHGLRR------YSFINCMFECRVRMTVDLCGCLPPYVYNNGSYKVCG 394
            ...|....:.|        |..|      ||.|.|...|..|.....|||  ..::..|:..||.
  Rat   291 DDFDPEPSDPL--------GSPRPRPSPPYSLIGCRLACESRYVARKCGC--RMMHMPGNSPVCS 345

  Fly   395 VLQ-TNCIIHSKRLFSHALANLNFSLSIVRETDSFPCGCLPDCQSNHYVSEST----TGRLDISY 454
            ..| .:|            |:......:.::|    |.|...|.:..|..|.:    ..|....|
  Rat   346 PQQYKDC------------ASPALDAMLRKDT----CVCPNPCATTRYAKELSMVRIPSRASARY 394

  Fly   455 FANRPTFNNA----TDRIL-LHVFFSDLMSTRYRTDIFQNWLSALASFGGLLGLIMGFSIVTAFE 514
            .|.:  :|.:    |:.:| |.:||..|................|...||.:||.:|.|::|..|
  Rat   395 LARK--YNRSESYITENVLVLDIFFEALNYEAVEQKAAYEVSELLGDIGGQMGLFIGASLLTILE 457

  Fly   515 FIYFL 519
            .:.:|
  Rat   458 ILDYL 462

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ppk16	NP_001334673.1	None
Asic3	XP_038963092.1	ASC	17..547	CDD:413546	115/525 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166345680
Domainoid	1	1.000	111	1.000	Domainoid score	I6095
eggNOG	1	0.900	-	-		E1_KOG4294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	75	1.000	Inparanoid score	I5173
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8907
orthoMCL	1	0.900	-	-		OOG6_100105
Panther	1	1.100	-	-	O	PTHR11690
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X60
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	8.790