Protein Alignment ppk16 and Asic2

DIOPT Version :10

• Sequence 1: NP_001334673.1
• Gene: ppk16 / 3885612
• FlyBaseID: FBgn0065108
• Length: 531
• Species: Drosophila melanogaster
• Sequence 2: NP_037024.2
• Gene: Asic2 / 25364
• RGDID: 2017
• Length: 563
• Species: Rattus norvegicus
• Alignment Length: 593
• Identity: 138/593 - (23%)
• Similarity: 213/593 - (35%)
• Gaps: 175/593 - (29%)

  Fly    17 QQMATTAIHRRSHPMHNHSHNP-IQPQHRFRQIGEWFTENMRNYCQTTSLHGFSYI----TRQDI 76
            :|.|..|:.....|..:.|.:| :|        |.......|.....|.|||..::    |....
  Rat    25 EQPAPVAVAAARQPGGDRSGDPALQ--------GPGVARRGRPSLSRTKLHGLRHMCAGRTAAGG 81

  Fly    77 SRHERWFWLVVVILAIITSIVLVVVSW------YWSQETPTVTVIESSHFPT-------WN--IP 126
            |...|..|    :||..||:.| ::||      ||..            ||:       |:  :|
  Rat    82 SFQRRALW----VLAFCTSLGL-LLSWSSNRLLYWLS------------FPSHTRVHREWSRQLP 129

  Fly   127 FPAVTICN-----FNKISKSKA------LSLLDQMQVPVGINRSELHNLFNLTLLPV--DTMISN 178
            |||||:||     |.::||...      |.||                |.|.|..|:  :.:..:
  Rat   130 FPAVTVCNNNPLRFPRLSKGDLYYAGHWLGLL----------------LPNRTARPLVSELLRGD 178

  Fly   179 DSLQKYDRILS-------------LNNLTLNRLTQQLSPDCIEMISSCIWKGINTRC-ESLFQRI 229
            :..:::.|.|:             ::...::||..||.    :|:.||.::|  ..| ...|..:
  Rat   179 EPRRQWFRKLADFRLFLPPRHFEGISAAFMDRLGHQLE----DMLLSCKYRG--ELCGPHNFSSV 237

  Fly   230 DTMEGQCCTFNYFGGISNNFPEKIAYQVPKRPYRVT---GCGYPTGLSVLLNPMISDY---YG-- 286
            .|..|:|..||  .|...            :|...|   |.|  .||.::|:....:|   :|
  Rat   238 FTKYGKCYMFN--SGEDG------------KPLLTTVKGGTG--NGLEIMLDIQQDEYLPIWGET 286

  Fly   287 --TFFSGFGFRLLLHDAYNFPDENSETKVVTTTRESFVRINP--ESTYATNDIRRMDL--SLRNC 345
              |.|.. |.::.:|       ..||...:   :|....:.|  ::..||.:.|...|  ....|
  Rat   287 EETTFEA-GVKVQIH-------SQSEPPFI---QELGFGVAPGFQTFVATQEQRLTYLPPPWGEC 340

  Fly   346 LFGSEMTMHGLRRYSFINCMFECRVRMTVDLCGCLPPYVYNNGSYKVCGVLQ-TNCIIHSKRLFS 409
            . .|||.:.....||...|..:|..|..|:.|.|  ..|:..|....|...| ..|
  Rat   341 R-SSEMGLDFFPVYSITACRIDCETRYIVENCNC--RMVHMPGDAPFCTPEQHKEC--------- 393

  Fly   410 HALANLNFSLSIVRETDSFPCGCLPDCQSNHYVSE----STTGRLDISYFANRPTFNNA----TD 466
                 ...:|.::.|.||..|.|...|....|..|    ....:....|...:  ||.:    ::
  Rat   394 -----AEPALGLLAEKDSNYCLCRTPCNLTRYNKELSMVKIPSKTSAKYLEKK--FNKSEKYISE 451

  Fly   467 RIL-LHVFFSDLMSTRYRTDIFQ----NWLSALASFGGLLGLIMGFSIVT---AFEFIYFLTFRP 523
            .|| |.:||..|   .|.| |.|    ...:.|...||.:||.:|.|::|   .|::||.|....
  Rat   452 NILVLDIFFEAL---NYET-IEQKKAYEVAALLGDIGGQMGLFIGASLLTILELFDYIYELIKEK 512

  Fly   524 VFNYINRE 531
            :.:.:.:|
  Rat   513 LLDLLGKE 520

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk16	NP_001334673.1	ASC	59..518	CDD:459966	126/535 (24%)
Asic2	NP_037024.2	ENaC	64..557	CDD:273304	129/546 (24%)