Protein Alignment ppk16 and Asic4

DIOPT Version :10

• Sequence 1: NP_001334673.1
• Gene: ppk16 / 3885612
• FlyBaseID: FBgn0065108
• Length: 531
• Species: Drosophila melanogaster
• Sequence 2: XP_036020902.1
• Gene: Asic4 / 241118
• MGIID: 2652846
• Length: 586
• Species: Mus musculus
• Alignment Length: 548
• Identity: 119/548 - (21%)
• Similarity: 184/548 - (33%)
• Gaps: 159/548 - (29%)

  Fly    55 NMRNYCQTTSLHGFSYITRQDISRHERWFWLVVVILAIITSIVLV------VVSWYWSQETPTVT 113
            ::..:..|::|||.............|..|    .||::||:...      :...|.::  |.:.
Mouse    41 DLATFASTSTLHGLGRACGPGPHGLRRTLW----ALALLTSLAAFLYQAASLARGYLTR--PHLV 99

  Fly   114 VIESSHFPTWNIP---FPAVTICNFNKISKSKALSLLDQMQVPVGINRSELHNLFNLTLLP---- 171
            .::    |....|   |||||:||.|:...|             .::.:::.:|.|||.||
Mouse   100 AMD----PAAPAPVAGFPAVTLCNINRFRHS-------------ALSDADIFHLANLTGLPPKDR 147

  Fly   172 ---------------VDTMISNDSLQKYDRILSLNNLTLNRLTQQLSPDCIEMISSCIWKGINTR 221
                           ||                    .|||...||:    :|:.||.:.|  ..
Mouse   148 DGHRAAGLRYPEPDMVD--------------------ILNRTGHQLA----DMLKSCNFSG--HH 186

  Fly   222 CE-SLFQRIDTMEGQCCTFNYFGGISNNFPEKIAYQVPKRPYRVTGCGYPTGLSVLLN------- 278
            |. |.|..:.|..|:|.|||             |......|.|..|.|  :||.::|:
Mouse   187 CSASNFSVVYTRYGKCYTFN-------------ADPQSSLPSRAGGMG--SGLEIMLDIQQEEYL 236

  Fly   279 PMISDYYGTFFSGFGFRLLLHDAYNFPDENSETKVVTTTRESFVRINPES-TYATNDIRRMDLSL 342
            |:..:...|.|.. |.|:.:|.....|..:.....|:...::||....:. ||       :....
Mouse   237 PIWRETNETSFEA-GIRVQIHSQEEPPYIHQLGFGVSPGFQTFVSCQEQRLTY-------LPQPW 293

  Fly   343 RNCLFGSEM---TMHGLRRYSFINCMFECRVRMTVDLCGCLPPYVYNNGSYKVCGV--------- 395
            .||...||:   .:.|...||...|...|.....:..|.|...::.......|.|.
Mouse   294 GNCRAESELREPELQGYSAYSVSACRLRCEKEAVLQRCHCRMVHMPGGHLQPVFGATLLSSRTSR 358

  Fly   396 ----LQTNCIIHSKRLFSH--ALANLNFSLSIVRET---------------DSF------PCGCL 433
                ::|.|    .|:::|  .|..::..|.:..||               ||.      ||.|.
Mouse   359 RQRCMRTTC----TRIYTHERVLMCMSGYLHMGNETICPPNIYIECADHTLDSLGGGSEGPCFCP 419

  Fly   434 PDCQSNHYVSE----STTGRLDISYFANRPTFNNATDR---ILLHVFFSDLMSTRYRTDIFQNWL 491
            ..|....|..|    ....|....|.|.:...|....|   ::|.|||..|.|............
Mouse   420 TPCNLTRYGKEISMVKIPNRGSARYLARKYNRNETYIRENFLVLDVFFEALTSEAMEQQAAYGLS 484

  Fly   492 SALASFGGLLGLIMGFSIVTAFEFIYFL 519
            :.|...||.:||.:|.||:|..|.:.::
Mouse   485 ALLGDLGGQMGLFIGASILTLLEILDYI 512

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk16	NP_001334673.1	ASC	59..518	CDD:459966	119/541 (22%)
Asic4	XP_036020902.1	ENaC	40..535	CDD:273304	119/548 (22%)