Protein Alignment ppk16 and asic5

DIOPT Version :10

• Sequence 1: NP_001334673.1
• Gene: ppk16 / 3885612
• FlyBaseID: FBgn0065108
• Length: 531
• Species: Drosophila melanogaster
• Sequence 2: XP_017951381.2
• Gene: asic5 / 100498195
• XenbaseID: XB-GENE-983430
• Length: 852
• Species: Xenopus tropicalis
• Alignment Length: 535
• Identity: 122/535 - (22%)
• Similarity: 206/535 - (38%)
• Gaps: 132/535 - (24%)

  Fly    31 MHNHSHNPIQPQHRFRQIGEWFTENMRNYCQTTSLHGFSYITRQDISRHERWF----WLVVVILA 91
            :..||...::.:.::.          ..:..:||.||...:.....|.....|    |..||
 Frog   369 LRKHSVPSLEERKKYN----------HGFATSTSFHGVHNLVENGGSGKNSKFRTAIWTSVV--- 420

  Fly    92 IITSIVLVVVSW--------YWSQETPTVTVIESSHFPTWNIPFPAVTICNFNKISKSKALSLLD 148
               |:.:::..|        |:|  .||.|.:...:..  ||.|||:|.||.|:. ::||::
 Frog   421 ---SVFIIMACWQVCTRVINYFS--WPTTTSVNVQYVE--NIDFPAITFCNLNRF-QTKAVN--- 474

  Fly   149 QMQVPVGINRSELHNLFNLTLLPVD-TMISND--SLQKYDRILSLN-NLTLNRLTQQ----LSPD 205
                    |.|....|:|:....:. |.|::|  .:|:....|.|| |.::...|:.    |:.
 Frog   475 --------NLSIAFFLWNIVSAVLHFTSIASDPGEMQEVTDFLKLNKNFSIKEFTKNYGFYLNN- 530

  Fly   206 CIEMISSCIWKGINTRCESLFQRIDTMEGQCCTFNYFGGISNNFPEKIAYQVPKRPYRVTGCGYP 270
              ..:..|.:.|.....|. |:.|.|..|.|.|||| ..:|.|             .|:|..|
 Frog   531 --STLLKCSFFGYPCYPED-FEHIFTEYGNCYTFNY-NTVSMN-------------KRITTAG-- 576

  Fly   271 TGLSVLLNPMISDYYGTFFSGF---GFRLLLHDAYNFPDENSETKVVTTTRESFVRINPESTYAT 332
            .|||||.:...:::......||   |...:||           :.:|....:.....:|...:|.
 Frog   577 RGLSVLFDIKQTEFTDEPSLGFVDAGISFVLH-----------SPLVPPRFDGLGLHSPAGMHAH 630

  Fly   333 NDIRRMDLSLRNCLFGS-----EMTMHGLRRYSFINCMFECRVRMTVDLCGCLPPYVYNNGSYKV 392
            ..:||....::...:|.     ::..|.:  ||...|:.||:.....:.|||:|..:..||  |.
 Frog   631 VSMRRFKTVIQEHPWGECNPSLKLKYHEI--YSTYGCLQECKSYYIQNECGCIPFLLPGNG--KE 691

  Fly   393 CGVLQT-NCIIHSKRLFSHALANLNFSLSIVRETDSFPCGCLPDCQSNHYVSESTTGRLDISY-- 454
            |.:.|. ||:  |:.|::...:.| .|:.....|...||             |.|.....|||
 Frog   692 CDLQQLYNCV--SRALYTIEKSEL-CSMGTYNSTCPVPC-------------EETDFPATISYST 740

  Fly   455 --------FANRPTFNNA----TDRILLHVFFSDLMSTRYRTDIFQNWLSA---LASFGGLLGLI 504
                    |.:.....:|    .:.:.:.:.:.::   .|:....|..|:|   |::.||.|||.
 Frog   741 FPSDKAAQFLSAKLSKSALYMRNNLVYIDIKYHEM---NYKIMKQQKALTASELLSNIGGQLGLF 802

  Fly   505 MGFSIVTAFEFIYFL 519
            .|.|::|..|.:.:|
 Frog   803 CGASMITIIEVLEYL 817

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk16	NP_001334673.1	ASC	59..518	CDD:459966	119/504 (24%)
asic5	XP_017951381.2	Inhibitor_I29	66..129	CDD:462410
		Peptidase_C1A	158..360	CDD:239068
		ASC	387..816	CDD:459966	119/504 (24%)