Protein Alignment ppk16 and asic1

DIOPT Version :10

• Sequence 1: NP_001334673.1
• Gene: ppk16 / 3885612
• FlyBaseID: FBgn0065108
• Length: 531
• Species: Drosophila melanogaster
• Sequence 2: XP_004912018.1
• Gene: asic1 / 100489966
• XenbaseID: XB-GENE-977699
• Length: 525
• Species: Xenopus tropicalis
• Alignment Length: 522
• Identity: 111/522 - (21%)
• Similarity: 193/522 - (36%)
• Gaps: 133/522 - (25%)

  Fly    55 NMRNYCQTTSLHGFSYITRQDISRHERWFWLVVVI--LAIITSIVLVVVSWYWSQETPTVTVIES 117
            :::.:...::|||.::|...:.....|..|::..:  |:::..:....:.:|:  |.|.||.::.
 Frog    16 SVQAFASGSTLHGLAHIFTYERFSCRRLIWVLCFLGSLSLLLYVCTERIIYYF--EYPHVTKLDE 78

  Fly   118 SHFPTWNIPFPAVTICN-----FNKISKS------KALSLLDQMQVPVGINRSELHNLFNLTLLP 171
            ...|  .:.|||||.||     |::::|:      :.||||:        ||.||
 Frog    79 ISTP--RMIFPAVTFCNLNEFRFSRVTKNDLYHAGELLSLLN--------NRYEL---------- 123

  Fly   172 VDTMISNDSLQK--YDRILSLN----NLTLNRLTQQLSPDCIEMISSCIWKGINTRCESLFQRID 230
            .|:.::::.:.:  .|:....|    ...:.....:...|..||:.||.::|.....:. |..:.
 Frog   124 PDSQLADEKVMEILQDKANFRNFKPKPFNMREFYDRTGHDIREMLLSCKYRGEECSVDD-FVPVF 187

  Fly   231 TMEGQCCTFNYFGGISNNFPEKIAYQVPKRPYRVTGCGYPTGLSVLLNPMISDY---YG----TF 288
            |..|:|.|||  .|.:.           :.|...|..|...||.::|:....:|   :|    |.
 Frog   188 TRYGKCYTFN--SGRNG-----------RSPLVTTKGGTGNGLELMLDIQQDEYLPVWGETDETS 239

  Fly   289 FSGFGFRLLLHDAYNFPDENSETKVVTTTRESFVRINPES-TYAT---NDIRRMDLSLRNCLFGS 349
            |.. |.::.:|.....|..:.....|....::||....:. ||..   .|.:           .|
 Frog   240 FEA-GIKVQIHSQDEPPFIDQLGFGVAPGFQTFVSCQEQRLTYLPPPWGDCK-----------SS 292

  Fly   350 EMTMHGLRRYSFINCMFECRVRMTVDLCGCLPPYVYNNGS------YKVCGVLQTNCIIHSKRLF 408
            .|.......||...|..:|..|..|:.|.|...::..:.:      ||.|.
 Frog   293 AMDSEFFDTYSISACRIDCETRYLVENCNCRMVHMPGDAAYCTPELYKECA-------------- 343

  Fly   409 SHALANLNFSLSIVRETDSFPCGCLPDCQSNHYVSE----STTGRLDISYFANRPTFNN-----A 464
                   :.:|..:.|.|:..|.|...|....|..|    ....:....|.|.:  :|.     |
 Frog   344 -------DPALDFLVEKDNDFCVCETPCNMTRYGKELSMVKIPSKASARYLAKK--YNKSEQYIA 399

  Fly   465 TDRILLHVFFSDLMSTRYRTDIFQ----NWLSALASFGGLLGLIMGFSIVTAFEFIYFLTFRPVF 525
            .:.::|.:||..|   .|.| |.|    .....|...||.:||.:|.||:|..|         :|
 Frog   400 ENILVLDIFFEAL---NYET-IEQKKAYEVAGLLGDIGGQMGLFIGASILTVLE---------LF 451

  Fly   526 NY 527
            :|
 Frog   452 DY 453

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk16	NP_001334673.1	ASC	59..518	CDD:459966	109/507 (21%)
asic1	XP_004912018.1	ENaC	18..507	CDD:273304	111/520 (21%)