DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13516 and litaf

DIOPT Version :9

Sequence 1:	NP_001033966.1	Gene:	CG13516 / 3885599	FlyBaseID:	FBgn0040658	Length:	168	Species:	Drosophila melanogaster
Sequence 2:	NP_001002184.1	Gene:	litaf / 431731	ZFINID:	ZDB-GENE-040704-23	Length:	163	Species:	Danio rerio

Alignment Length:	163	Identity:	42/163 - (25%)
Similarity:	68/163 - (41%)	Gaps:	26/163 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 PTAPSPTPTRELGNPIANGLPIEAPPSYD-VAVSVPVAPAVSAPA--IAPARPPPVVVVEQPAPQ 78
            ||||....|..:|:|        .||||| ::.:.|..||...|.  :..:.|||....|.....
Zfish     6 PTAPPMENTTLVGHP--------PPPSYDEISGANPYYPAGPYPPADMKASGPPPYPTQEYNQMY 62

  Fly    79 PPT---------VVPTDTLHLGPN------RSRVLCPACGANKTTRMTHTANSRTHMVAGLLCLV 128
            |||         ||...|:::.|.      ..:..||.|..:..||:.:::.....:....|.:.
Zfish    63 PPTAQGQPVTSPVVAVQTVYVQPGLVFGNVPVQAHCPVCSQSVITRLEYSSGPLVWLSCAGLAVF 127

  Fly   129 GFCCCACFVPYCMNSCRTGNHYCRKCNTFLGAY 161
            |.....|.:|:|:...:...|:|..|::.||.:
Zfish   128 GCIYGCCLIPFCIEDLKDVTHHCPNCSSVLGVH 160

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13516	NP_001033966.1	zf-LITAF-like	96..162	CDD:287559	15/66 (23%)
litaf	NP_001002184.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..23		7/24 (29%)
		PPxY motif. /evidence=ECO:0000250\|UniProtKB:Q99732	22..25		2/2 (100%)
		zf-LITAF-like	93..161	CDD:287559	15/68 (22%)
		Membrane-binding amphipathic helix. /evidence=ECO:0000305	116..136		3/19 (16%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170578982
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54946
OrthoDB	1	1.010	-	-		D1564782at2759
OrthoFinder	1	1.000	-	-		FOG0000358
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23292
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.960