DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr13 and Igsf9

DIOPT Version :9

Sequence 1:	NP_001033956.2	Gene:	dpr13 / 3885598	FlyBaseID:	FBgn0034286	Length:	419	Species:	Drosophila melanogaster
Sequence 2:	NP_001139272.1	Gene:	Igsf9 / 93842	MGIID:	2135283	Length:	1179	Species:	Mus musculus

Alignment Length:	201	Identity:	49/201 - (24%)
Similarity:	83/201 - (41%)	Gaps:	39/201 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   185 VTTQIGATAHVPCTV----HHIGEGVVSWIRKKDYHLLTV----GLTTYSSDERFSATHLKHSED 241
            |..:.|.:|.:.|.:    .|....|:.|:|..  .||.:    ||.:...|..: ...::....
Mouse    29 VVGRAGESAVLGCDLLPPAGHPPLHVIEWLRFG--FLLPIFIQFGLYSPRIDPDY-VGRVRLQTG 90

  Fly   242 WTLQIKFVQLRDAGVYECQV---STHPPTSIF-----LHLSVVEARAEITGPPIRYLTPGSTLRL 298
            .:|||:.:::.|.|.|||:|   ..|.|...|     :||:|       ..||....||...|.:
Mouse    91 ASLQIEGLRVEDQGWYECRVLFLDQHSPEQDFANGSWVHLTV-------NSPPQFQETPPLVLEV 148

  Fly   299 Q------CRVVQNTEASEYIFWYHDNRMINYDIDRGINVSTEPDFQSSELTIQRTRREHSGNFTC 357
            :      .|.|.......|:.|    :....|:.:|   ..:...|:..|.|:|..|..:|::||
Mouse   149 KELEAVTLRCVARGSPQPYVTW----KFRGQDLGKG---QGQVQVQNGTLWIRRVERGSAGDYTC 206

  Fly   358 VASNTQ 363
            .||:::
Mouse   207 QASSSE 212

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr13	NP_001033956.2	V-set	180..276	CDD:284989	27/106 (25%)
		IG_like	182..262	CDD:214653	22/87 (25%)
		IG_like	285..362	CDD:214653	21/82 (26%)
		IGc2	292..361	CDD:197706	17/74 (23%)
Igsf9	NP_001139272.1	IG_like	28..110	CDD:214653	21/83 (25%)
		Ig	136..223	CDD:386229	20/84 (24%)
		Ig_3	227..305	CDD:372822
		Ig	341..404	CDD:386229
		Ig	436..500	CDD:319273
		FN3	508..599	CDD:238020
		FN3	625..715	CDD:238020
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	767..807
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	819..842
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	942..974
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1016..1079
		PDZ-binding	1177..1179
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900