DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr13 and igsf9bb

DIOPT Version :9

Sequence 1:	NP_001033956.2	Gene:	dpr13 / 3885598	FlyBaseID:	FBgn0034286	Length:	419	Species:	Drosophila melanogaster
Sequence 2:	XP_009293693.1	Gene:	igsf9bb / 569554	ZFINID:	ZDB-GENE-091112-15	Length:	1439	Species:	Danio rerio

Alignment Length:	373	Identity:	76/373 - (20%)
Similarity:	129/373 - (34%)	Gaps:	87/373 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 FIIAYIAACGICDHTASASPGGGKTVAATMTTPASE------PSVRHIN-QNLIMSQSKEGEPVP 84
            ::...||:......||:....|.:.....:|:.|.|      ..|..:| |..::...|.|.|:|
Zfish     4 YVATLIASVFSTRGTAAQGAHGVREEPQFVTSRAGETVILGCDVVHPLNGQPYVVEWFKFGVPIP 68

  Fly    85 -----------VPQPYAQSAASAGGSSITSFDSTNVIDGQSQPTPTHLQEAVLQTHSHSRIQAKD 138
                       |...||..|:..|.||:..                            .|::::|
Zfish    69 FFINFRFYPPHVDPEYAGRASLHGKSSLRI----------------------------ERVRSED 105

  Fly   139 TAGPYPIPVHRPEPVENHLEANNGIEGGMESLFGTPMYFGTENSTVVTTQIGATAHVPCTVHHIG 203
             .|.|...|...|  :.:...:||  ..:......|..|.......|..:.|.:..:.||.....
Zfish   106 -QGWYECKVLMLE--QQYHTFHNG--SWVHLTVNAPPTFTDTPPQYVEAKEGGSITLSCTAFGNP 165

  Fly   204 EGVVSWIRKKDYHLLTVGLTTYSSDERFSATHLKHSEDWTLQIKFVQLRDAGVYECQVSTHPPTS 268
            :..|||:|:        |.....|      |..|.| |.:|.:..:...|.|.|.|:..:....:
Zfish   166 KPSVSWLRE--------GNPVQDS------TKYKVS-DGSLTLVSISREDRGAYTCRAYSEQGEA 215

  Fly   269 IFLHLSVVEARAEITGPPIRYLTPGS-TLRLQCRVVQNTEASEY-------IFWYHDNRMINYDI 325
            :  |.:    |..:.|||.....|.: |:.:........:|..|       .||..||.....|:
Zfish   216 V--HTT----RLLVQGPPFIVSPPENITVNISQDAFFTCQAEAYPGNLTYTWFWEEDNVFFKNDL 274

  Fly   326 DRGINVSTEPDFQSSELTIQRTRREHSGNFTCVASNT--QPASVLVHI 371
            .|.:::..:     ..|.|.:.:.|.:|.:||..||:  :|.|...::
Zfish   275 KRRVSILID-----GSLIISQVKPEDAGKYTCSPSNSLGRPPSASAYL 317

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr13	NP_001033956.2	V-set	180..276	CDD:284989	20/95 (21%)
		IG_like	182..262	CDD:214653	19/79 (24%)
		IG_like	285..362	CDD:214653	19/84 (23%)
		IGc2	292..361	CDD:197706	16/76 (21%)
igsf9bb	XP_009293693.1	IG_like	30..113	CDD:214653	21/111 (19%)
		Ig	41..113	CDD:143165	18/100 (18%)
		IG_like	144..223	CDD:214653	21/99 (21%)
		IGc2	151..208	CDD:197706	18/71 (25%)
		I-set	227..319	CDD:254352	21/96 (22%)
		Ig	<263..319	CDD:299845	15/60 (25%)
		Ig_2	326..414	CDD:290606
		IG_like	329..403	CDD:214653
		IG_like	424..504	CDD:214653
		Ig	440..504	CDD:299845
		FN3	509..604	CDD:238020
		FN3	620..704	CDD:238020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910