DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr13 and dscama

DIOPT Version :9

Sequence 1:	NP_001033956.2	Gene:	dpr13 / 3885598	FlyBaseID:	FBgn0034286	Length:	419	Species:	Drosophila melanogaster
Sequence 2:	XP_021334866.1	Gene:	dscama / 568643	ZFINID:	ZDB-GENE-050310-7	Length:	2025	Species:	Danio rerio

Alignment Length:	317	Identity:	77/317 - (24%)
Similarity:	116/317 - (36%)	Gaps:	80/317 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    87 QPYAQSAASAGGSSITSFDSTNV------------IDGQSQP--TPTHLQEAVLQTHSH------ 131
            |.:.|.....|...|.|..|..|            :.|..||  |.|...|.|.:...|
Zfish   396 QDFVQVILEDGTPKILSAFSEKVVGPNDFVSLTCHVKGTPQPAITWTLDDEVVAKDSRHRIVHSI 460

  Fly   132 ------------SRIQAKDTAGPYPIPVHRPEPVENHLEANNGIEGGMESLFGTPMYFGTENSTV 184
                        |.||.:| :|.|....:......:: :|...:.|..:.   .||    :|.|.
Zfish   461 TAEGNVVSYLNISHIQVRD-SGVYRCTCNNSAGTVSY-QARINVRGSADI---RPM----KNLTA 516

  Fly   185 VTTQIGATAHVPCTVHHIGEGV--VSWIRKKDYHLLTVGLTTYSSDERFSATHLKHSEDWTLQIK 247
            :.   |...::.|  |.||...  :.|.  |:.:||.           |:........:.||::.
Zfish   517 IA---GWDMYIHC--HVIGYPYYSIKWF--KNSNLLP-----------FNDRQRAFENNGTLKLL 563

  Fly   248 FVQLR-DAGVYECQVSTHPPTSIFLHLSVVEARAEITGPPI-------RYLTPGSTLRLQCRVVQ 304
            .||.. |.|.|.|.|...|  .:|.:.||   ...:..||.       || :.|..:.:.| ||:
Zfish   564 NVQKELDEGEYSCHVQVQP--QLFKNQSV---HVTVKVPPFIQPFEFPRY-SIGHRVFVPC-VVR 621

  Fly   305 NTEASEYIFWYHDNRMINYDIDRGINVSTEPDFQSSELTIQRTRREHSGNFTCVASN 361
            :.:....|.|..|.:.||..:  |:.:. ..||.|| |.|...:|.|:|.:||:|.|
Zfish   622 SGDLPISITWEKDGKSINASL--GVTID-NIDFTSS-LRISNLQRVHNGTYTCIAQN 674

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr13	NP_001033956.2	V-set	180..276	CDD:284989	24/98 (24%)
		IG_like	182..262	CDD:214653	19/82 (23%)
		IG_like	285..362	CDD:214653	27/84 (32%)
		IGc2	292..361	CDD:197706	22/68 (32%)
dscama	XP_021334866.1	Ig	124..217	CDD:325142
		I-set	236..311	CDD:254352
		IG_like	321..402	CDD:214653	2/5 (40%)
		I-set	408..502	CDD:333254	19/95 (20%)
		IGc2	524..579	CDD:197706	17/69 (25%)
		Ig	614..679	CDD:319273	22/66 (33%)
		Ig_DSCAM	708..787	CDD:143211
		Ig	805..898	CDD:325142
		FN3	894..988	CDD:238020
		FN3	995..1092	CDD:238020
		fn3	1100..1186	CDD:306538
		fn3	1199..1282	CDD:306538
		Ig	1312..1377	CDD:319273
		fn3	1405..1471	CDD:306538
		FN3	1492..1563	CDD:238020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810