DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr13 and sdk1a

DIOPT Version :9

Sequence 1:	NP_001033956.2	Gene:	dpr13 / 3885598	FlyBaseID:	FBgn0034286	Length:	419	Species:	Drosophila melanogaster
Sequence 2:	XP_009297968.1	Gene:	sdk1a / 558391	ZFINID:	ZDB-GENE-081104-374	Length:	2245	Species:	Danio rerio

Alignment Length:	174	Identity:	45/174 - (25%)
Similarity:	68/174 - (39%)	Gaps:	17/174 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   185 VTTQIGATAHVPCTVHHIGEGVVSWIRKKDYHLLTVGLTTYSSDERFSATHLKHSEDWTLQIKFV 249
            :|...||.|...|.|....:..:.|  ::|..:|..|....   .||:..     |...|||:.|
Zfish   519 ITVTDGAVAAFTCRVSGAPKPAIVW--RRDTQILASGSVQI---PRFTLL-----ESGGLQIQPV 573

  Fly   250 QLRDAGVYECQVSTHPPTSIFLHLSVVEARAEITGPPI-RYLTPGSTLRLQCRVVQNTEASEYIF 313
            .|:|.|.|.|..:.............|.:|..|:.||. |.:..|:|..|:|....:........
Zfish   574 VLQDTGNYTCYAANSEGAINASASLTVWSRTSISSPPTDRRVIKGTTAILECGATHDPRVGVRYV 638

  Fly   314 WYHDNRMINYDIDRGINVSTEPDFQSSELTIQRTRREHSGNFTC 357
            |..|..::::  .||..:|    .|...|.|.:|.....||:||
Zfish   639 WKKDEELVSH--SRGGRIS----LQEGSLHISQTWSGDIGNYTC 676

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr13	NP_001033956.2	V-set	180..276	CDD:284989	22/90 (24%)
		IG_like	182..262	CDD:214653	22/76 (29%)
		IG_like	285..362	CDD:214653	20/74 (27%)
		IGc2	292..361	CDD:197706	17/66 (26%)
sdk1a	XP_009297968.1	I-set	125..208	CDD:254352
		Ig	125..204	CDD:299845
		IG_like	222..302	CDD:214653
		Ig	236..287	CDD:299845
		Ig_3	322..394	CDD:290638
		I-set	323..412	CDD:254352
		I-set	416..505	CDD:254352
		Ig	436..500	CDD:299845
		I-set	510..600	CDD:254352	22/90 (24%)
		Ig	527..600	CDD:299845	19/82 (23%)
		I-set	605..693	CDD:254352	21/78 (27%)
		Ig	610..693	CDD:299845	19/73 (26%)
		FN3	697..788	CDD:238020
		fn3	800..886	CDD:278470
		FN3	901..997	CDD:238020
		FN3	1002..1090	CDD:238020
		FN3	1100..1196	CDD:238020
		FN3	1206..1301	CDD:238020
		FN3	1308..1397	CDD:238020
		FN3	1408..1501	CDD:238020
		FN3	1507..1602	CDD:238020
		FN3	1616..1722	CDD:238020
		FN3	1732..1825	CDD:238020
		FN3	1830..1919	CDD:238020
		FN3	1931..2021	CDD:238020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810