DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr13 and igsf9a

DIOPT Version :9

Sequence 1:	NP_001033956.2	Gene:	dpr13 / 3885598	FlyBaseID:	FBgn0034286	Length:	419	Species:	Drosophila melanogaster
Sequence 2:	XP_005155702.1	Gene:	igsf9a / 557459	ZFINID:	ZDB-GENE-060503-288	Length:	1619	Species:	Danio rerio

Alignment Length:	343	Identity:	78/343 - (22%)
Similarity:	112/343 - (32%)	Gaps:	89/343 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    58 TPASEPSVRHINQNLIMSQSKEGEPVPVPQPYAQSAASAGGSSITSFDSTNVID--GQSQPTPTH 120
            |.|:|..||      ....|....|..:|.|...|:|           |..||:  .|...||..
Zfish    22 TSAAEEHVR------AKKDSSAVLPCSLPAPQKDSSA-----------SQYVIEWVRQGFDTPIF 69

  Fly   121 LQEAVLQTHSHSRI---------------------QAKDTAGPYPIPVHRPEPVENHLEANNGIE 164
            :|..|     |.|:                     |.:| .|.|..   |..|::...| ..|..
Zfish    70 MQLGV-----HPRVHPDYDGRVSLFGGTSLQMSGLQLED-EGWYEC---RILPLDQTTE-EAGSS 124

  Fly   165 GGMESLFGTPMYFGTENS-TVVTTQIGATAHVPCTVHHIGEGVVSWIRKKDYHLLTVGLTTYSSD 228
            |....|..|.....||.| ..|...:|.:..:.|.........::|  .||             .
Zfish   125 GSWTRLSVTAPPVLTETSPPEVEVFVGRSLTLKCAAQGNPRPTITW--SKD-------------G 174

  Fly   229 ERFSATHLKHSEDWTLQIKFVQLRDAGVYECQVSTHPPTSIFLHLSVVEARAEITGPPIRYLTPG 293
            ......|.....:.::....|....||.|:|..|.....:  .|::    |.:|.|||:..:.|.
Zfish   175 APIKPQHKVKMVNGSVSFHAVSREAAGQYQCYTSNSEGNA--THVT----RLKIIGPPVIIIPPS 233

  Fly   294 STL-------RLQCRVVQNTEASEYIFWYHDNRMINYDID---RGINVSTEPDFQSSELTIQRTR 348
            .|:       :|:|:...:.....|: |......| |.||   ..|.|..:     ..|.|.|..
Zfish   234 DTVLNMSQDAKLKCQAEADPPNMTYV-WQRQGVDI-YHIDSLKSRIKVIVD-----GTLLISRLA 291

  Fly   349 REHSGNFTCVASNTQPAS 366
            .|.|||:||:.:|..|.|
Zfish   292 PEDSGNYTCMPTNGLPVS 309

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr13	NP_001033956.2	V-set	180..276	CDD:284989	16/96 (17%)
		IG_like	182..262	CDD:214653	13/80 (16%)
		IG_like	285..362	CDD:214653	23/86 (27%)
		IGc2	292..361	CDD:197706	21/78 (27%)
igsf9a	XP_005155702.1	IG_like	27..110	CDD:214653	22/108 (20%)
		Ig	35..111	CDD:299845	20/95 (21%)
		I-set	140..221	CDD:254352	17/101 (17%)
		IGc2	151..212	CDD:197706	12/75 (16%)
		Ig	233..318	CDD:299845	23/84 (27%)
		I-set	233..318	CDD:254352	23/84 (27%)
		Ig	<349..402	CDD:299845
		IG_like	423..502	CDD:214653
		Ig	435..498	CDD:143165
		FN3	507..602	CDD:238020
		fn3	614..696	CDD:278470
		PHA02666	1105..>1312	CDD:222914
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900