DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr13 and iglon5

DIOPT Version :9

Sequence 1:	NP_001033956.2	Gene:	dpr13 / 3885598	FlyBaseID:	FBgn0034286	Length:	419	Species:	Drosophila melanogaster
Sequence 2:	NP_001017775.2	Gene:	iglon5 / 550472	ZFINID:	ZDB-GENE-050417-297	Length:	332	Species:	Danio rerio

Alignment Length:	298	Identity:	66/298 - (22%)
Similarity:	100/298 - (33%)	Gaps:	117/298 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly   190 GATA----HVPCTVHHI-GEGVV------------SWIRKKDYHLLTVGLTTYSSDERFSATHLK 237
            ||.|    |:|..:..: ||.||            :|:.:.  ::|..|...:|.|.|.|..: .
Zfish    23 GAQAAEFGHLPDNITVLEGESVVLRCKIDEEVTHKAWLNRS--NILFTGTDKWSLDSRVSLEN-N 84

  Fly   238 HSEDWTLQIKFVQLRDAGVYEC--QVSTHPPTSIFLHLSVVEAR--------------------- 279
            ::.|::::|:.|.:.|.|.|.|  |....|.|:....:..|.||
Zfish    85 NNSDFSIRIERVMVADEGPYTCSFQARNKPRTAHVYLIVQVPARIVNISQDKSVNEGEDVNLFCL 149

  Fly   280 ------------------------AEIT------------------GPP--------IRY---LT 291
                                    .|||                  .||        :.|   :|
Zfish   150 AVGRPEPTITWKDFKYGLLNEGEFLEITEIKRHQAEDFECITNNGVAPPDTRKVKVTVNYPPIIT 214

  Fly   292 P--------GSTLRLQCRVVQNTEASEYIFWYHDNRMINYDIDRGINVSTEPDFQSSELTIQRTR 348
            .        |.|..|:|..:....||  ..||.|:|. ..:.|..:.:..|.  ..|.|......
Zfish   215 DVKNMPAQVGKTAILRCEAMAVPTAS--FEWYRDDRR-PVESDNTLKIKNEK--TRSLLLFTNVT 274

  Fly   349 REHSGNFTCVASN---TQPASVLVHIFKGDNPAAMYHG 383
            .:|.||:||.|||   ...||:|  :|:   |.|:|.|
Zfish   275 EKHFGNYTCFASNRLGASNASML--LFR---PGAVYGG 307

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr13	NP_001033956.2	V-set	180..276	CDD:284989	26/104 (25%)
		IG_like	182..262	CDD:214653	24/90 (27%)
		IG_like	285..362	CDD:214653	26/98 (27%)
		IGc2	292..361	CDD:197706	20/76 (26%)
iglon5	NP_001017775.2	IG_like	33..123	CDD:214653	22/92 (24%)
		Ig	35..123	CDD:299845	21/90 (23%)
		Ig	125..>183	CDD:299845	6/57 (11%)
		I-set	128..207	CDD:254352	6/78 (8%)
		IG_like	217..298	CDD:214653	25/87 (29%)
		ig	223..296	CDD:278476	23/77 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910