DRSC/TRiP Functional Genomics Resources

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Protein Alignment dpr13 and NTM

DIOPT Version :9

Sequence 1:NP_001033956.2 Gene:dpr13 / 3885598 FlyBaseID:FBgn0034286 Length:419 Species:Drosophila melanogaster
Sequence 2:NP_001338930.1 Gene:NTM / 50863 HGNCID:17941 Length:367 Species:Homo sapiens


Alignment Length:196 Identity:52/196 - (26%)
Similarity:88/196 - (44%) Gaps:40/196 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly   185 VTTQIGATAHVPCTV-HHIGEGVVSWIRKKDYHLLTVGLTTYSSDER---FSATHLKHSEDWTLQ 245
            ||.:.|.:|.:.||: :.:..  |:|:.:..  :|..|...:..|.|   .|.|..::|    ::
Human    45 VTVRQGESATLRCTIDNRVTR--VAWLNRST--ILYAGNDKWCLDPRVVLLSNTQTQYS----IE 101

  Fly   246 IKFVQLRDAGVYECQVST--HPPTSIFLHL------SVVEARAEITGPPIRYLTPGSTLRLQCRV 302
            |:.|.:.|.|.|.|.|.|  ||.|| .:||      .:||..::|:      :..|:.:.|.|..
Human   102 IQNVDVYDEGPYTCSVQTDNHPKTS-RVHLIV
QVSPKIVEISSDIS------INEGNNISLTCIA 159

  Fly   303 VQNTEASEYIFWYHDNRMINYDIDRGINVSTEPDFQSSELTIQRTRREHSGNFTCVASNTQPASV 367
            ....|.:  :.|.|.:       .:.:...:|.::    |.||...||.||::.|.|||...|.|
Human   160 TGRPEPT--VTWRHIS-------PKAVGFVSEDEY----LEIQGITREQSGDYECSASNDVAAPV 211

  Fly   368 L 368
            :
Human   212 V 212

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dpr13NP_001033956.2 V-set 180..276 CDD:284989 29/102 (28%)
IG_like 182..262 CDD:214653 21/80 (26%)
IG_like 285..362 CDD:214653 17/76 (22%)
IGc2 292..361 CDD:197706 16/68 (24%)
NTMNP_001338930.1 Ig 44..132 CDD:416386 29/95 (31%)
Ig strand A' 44..49 CDD:409353 2/3 (67%)
Ig strand B 51..59 CDD:409353 2/7 (29%)
CDR1 59..63 CDD:409353 0/3 (0%)
FR2 64..70 CDD:409353 2/7 (29%)
Ig strand C 64..70 CDD:409353 2/7 (29%)
CDR2 71..83 CDD:409353 2/13 (15%)
Ig strand C' 72..76 CDD:409353 0/5 (0%)
Ig strand C' 80..83 CDD:409353 0/2 (0%)
FR3 84..118 CDD:409353 11/37 (30%)
Ig strand D 87..94 CDD:409353 2/6 (33%)
Ig strand E 97..103 CDD:409353 1/9 (11%)
Ig strand F 110..118 CDD:409353 3/7 (43%)
CDR3 119..123 CDD:409353 1/3 (33%)
Ig strand G 123..132 CDD:409353 5/9 (56%)
FR4 125..132 CDD:409353 4/7 (57%)
Ig_3 136..205 CDD:404760 19/87 (22%)
Ig strand A' 142..147 CDD:409353 1/10 (10%)
Ig strand B 153..160 CDD:409353 2/6 (33%)
Ig strand C 166..171 CDD:409353 1/6 (17%)
Ig strand D 177..180 CDD:409353 0/2 (0%)
Ig strand E 184..190 CDD:409353 2/9 (22%)
Ig strand F 197..204 CDD:409353 2/6 (33%)
Ig strand G 211..219 CDD:409353 1/2 (50%)
Ig_3 222..299 CDD:404760
putative Ig strand A 223..229 CDD:409353
Ig strand B 239..243 CDD:409353
Ig strand C 252..256 CDD:409353
Ig strand E 278..282 CDD:409353
Ig strand F 292..297 CDD:409353
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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