DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr13 and tutl

DIOPT Version :9

Sequence 1:	NP_001033956.2	Gene:	dpr13 / 3885598	FlyBaseID:	FBgn0034286	Length:	419	Species:	Drosophila melanogaster
Sequence 2:	NP_001303307.1	Gene:	tutl / 46015	FlyBaseID:	FBgn0010473	Length:	1536	Species:	Drosophila melanogaster

Alignment Length:	420	Identity:	85/420 - (20%)
Similarity:	137/420 - (32%)	Gaps:	126/420 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 GICDHTASASPGGGKTVAATMTTPASEPSVRHINQNLIMSQSKEGEPVPVPQPYAQSAASAGG-- 98
            |:|     |..|..:...|..|...:|.|         ..|.::.:|:.:|:   |.|:...|
  Fly     2 GVC-----ADLGSHRWCRALSTQHNTEKS---------KEQQQQSQPLEIPE---QRASKCRGDI 49

  Fly    99 --SSITSFDSTNVIDGQSQPTPTHLQEAVLQTHSHSRIQAKDTAGPYPIPVHR-----PEPVENH 156
              ::.|:..::..:......|.....:...:..|..|.:.....    :|:.|     |.|....
  Fly    50 DRTTTTTIPASKTLTASPAKTAAFTVKTTRRRRSRRRAEGSSIC----VPIRRGQGSTPTPTIQV 110

  Fly   157 LE----------ANNGIEGGMESLFGTPMYFGTENSTVVTTQIGATAHVPCTVHHIGEGVVSWIR 211
            |:          |.|.      .....|     |::..:|..:|......|.|....:..|.::.
  Fly   111 LQFVLVSLLALLAKNA------QAHNIP-----EDAVHITAILGEGVIFNCHVEFPNDHPVPYVL 164

  Fly   212 KKDYHLLTVG-----LTTYSS-----DERFSATHLKHSED-----WTLQIKFVQLRDAGVYECQV 261
            :.|..:...|     ...|.|     :|.:.....:.|:|     .:|.:..::..|.|.|||:|
  Fly   165 QWDKKVSETGSDLPIYIWYESYPEHIEEGYKGRVSRVSQDSPFGSASLNLTNIRESDQGWYECKV 229

  Fly   262 STHPPTSIFL-------------HLSV-VEARAEITGPPIRYLTPGSTLRLQCRVVQNTEASEYI 312
                   :||             ||.| ...|..:|...|.|:..|.::.|.|: ...|...| |
  Fly   230 -------VFLNRDPKQHKNGTWFHLDVHAPPRFSVTPEDIIYVNLGDSIILNCQ-ADGTPTPE-I 285

  Fly   313 FWYHDNRMINYDIDRGI-NVSTEPDFQSSELTIQRTRREHSGNFTCVASNTQPASVLVHIFKGDN 376
            .||.|...::.....|| |..|       ||.|...|.|..|.:||:|.|.:
  Fly   286 LWYKDANPVDPSPTVGIFNDGT-------ELRISTIRHEDIGEYTCIARNGE------------- 330

  Fly   377 PAAMYHGHVGGSTKTTQSQLHMIMIIIASG 406
                  |.|.          |...:|||.|
  Fly   331 ------GQVS----------HTARVIIAGG 344

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr13	NP_001033956.2	V-set	180..276	CDD:284989	25/124 (20%)
		IG_like	182..262	CDD:214653	18/94 (19%)
		IG_like	285..362	CDD:214653	24/77 (31%)
		IGc2	292..361	CDD:197706	22/69 (32%)
tutl	NP_001303307.1	V-set	137..250	CDD:284989	23/119 (19%)
		IG_like	137..229	CDD:214653	18/91 (20%)
		I-set	253..341	CDD:254352	30/125 (24%)
		IGc2	268..331	CDD:197706	23/90 (26%)
		I-set	346..437	CDD:254352
		Ig	349..437	CDD:299845
		Ig	459..530	CDD:299845
		IG_like	549..628	CDD:214653
		IGc2	551..617	CDD:197706
		FN3	633..725	CDD:238020
		FN3	786..874	CDD:238020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810