DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr13 and cadm2

DIOPT Version :9

Sequence 1:	NP_001033956.2	Gene:	dpr13 / 3885598	FlyBaseID:	FBgn0034286	Length:	419	Species:	Drosophila melanogaster
Sequence 2:	XP_031751706.1	Gene:	cadm2 / 448238	XenbaseID:	XB-GENE-998536	Length:	441	Species:	Xenopus tropicalis

Alignment Length:	232	Identity:	50/232 - (21%)
Similarity:	91/232 - (39%)	Gaps:	58/232 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   179 TENSTVVTTQIGATAHVPCTVHHIGEGVVSWIRKKDYHLLTVGLTTYSSDE---RFSATHLKHSE 240
            |:|.|||.   |.|.::.|.|.......:.|......       |.|..|:   |.:...|..:
Frog    37 TQNVTVVE---GGTINLTCRVDQNDNTSLQWSNPAQQ-------TLYFDDKKALRDNRIELVRA- 90

  Fly   241 DW---TLQIKFVQLRDAGVYECQVSTHPPTSIFLHLSV--VEARAEITGPPIRYLTP---GSTLR 297
            .|   ::.|..|.|.|.|.|.|.:.|.|..:...:|.|  |.....|:|    :.:|   |.|::
Frog    91 SWHELSISISDVSLSDEGQYTCSLFTMPVKTSKAYLMVLGVPENPHISG----FTSPVMEGDTIQ 151

  Fly   298 LQCRVVQNTEASEYIFWYHDNRMINYDIDRGINVSTEPDFQSSELT-IQRTRREHSGNFTCVASN 361
            |.|:...:..|:: |.|:.:::                     |:| :|:.:::.|...|...::
Frog   152 LTCKSSGSKPAAD-IRWFKNDQ---------------------EITDVQKIQQQDSNGKTFTVTS 194

  Fly   362 TQPASVLVHIFKGD--NPAAMYHGHVGGSTKTTQSQL 396
            :.       :|:||  :..|:....|...:.|:..|:
Frog   195 SL-------VFQGDRKDDGAVIRCRVDHESLTSTPQI 224

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr13	NP_001033956.2	V-set	180..276	CDD:284989	26/103 (25%)
		IG_like	182..262	CDD:214653	21/85 (25%)
		IG_like	285..362	CDD:214653	13/80 (16%)
		IGc2	292..361	CDD:197706	13/72 (18%)
cadm2	XP_031751706.1	IgV_1_Necl-3	34..129	CDD:409498	26/102 (25%)
		Ig strand B	48..52	CDD:409498	0/3 (0%)
		Ig strand C	61..65	CDD:409498	0/3 (0%)
		Ig strand E	95..99	CDD:409498	0/3 (0%)
		Ig strand F	109..114	CDD:409498	2/4 (50%)
		Ig strand G	121..124	CDD:409498	0/2 (0%)
		IgI_2_Necl-3	128..231	CDD:409467	24/130 (18%)
		Ig strand B	150..154	CDD:409467	1/3 (33%)
		Ig strand C	164..168	CDD:409467	1/4 (25%)
		Ig strand E	194..198	CDD:409467	0/10 (0%)
		Ig strand F	208..213	CDD:409467	0/4 (0%)
		Ig strand G	224..227	CDD:409467	0/1 (0%)
		IGc2	248..311	CDD:197706
		Ig strand B	250..259	CDD:409353
		Ig strand C	265..271	CDD:409353
		Ig strand C'	274..277	CDD:409353
		Ig strand D	280..285	CDD:409353
		Ig strand E	286..293	CDD:409353
		Ig strand F	300..308	CDD:409353
		Ig strand G	311..321	CDD:409353
		4.1m	394..412	CDD:128590
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	82	1.000	Inparanoid score	I5030
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.960