DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr13 and dpr17

DIOPT Version :9

Sequence 1:	NP_001033956.2	Gene:	dpr13 / 3885598	FlyBaseID:	FBgn0034286	Length:	419	Species:	Drosophila melanogaster
Sequence 2:	NP_001287297.1	Gene:	dpr17 / 41470	FlyBaseID:	FBgn0051361	Length:	664	Species:	Drosophila melanogaster

Alignment Length:	416	Identity:	115/416 - (27%)
Similarity:	181/416 - (43%)	Gaps:	82/416 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 AACGICDHTASASPGGGKTVAATMTT----PASEPSVRHINQNLIMSQSKEGE------------ 81
            ||.......|.||.......||.|..    |||..:..|   |.|  :..||:
  Fly   254 AATSAATSAAIASAAAATETAAEMLISTIYPASTETDLH---NSI--ERVEGQRGKMANAFHPGV 313

  Fly    82 ---------------PVPV----PQPYAQSAASAGGSSITSFDSTNVIDGQSQPTPTHLQEAVLQ 127
                           |.||    ..|..::||.|..::..:.::.    .|:....|. .|||..
  Fly   314 PDSLTKGFSIPTFLPPFPVFAAADLPAYRAAADAAEAAKLAAEAA----AQAAAAKTS-SEAVTM 373

  Fly   128 THSHSRIQAKDTAGPYPIPVHRPEPVENHLEANNGIEGGMESLFGTPMYFGTENSTV----VTTQ 188
            :....|.|..:....| :..||           :|.:|...::        ..|.|:    :|.|
  Fly   374 SPEEQRRQMFNEQHSY-LAAHR-----------DGGDGAGSAV--------RRNLTMPVLNITAQ 418

  Fly   189 IGATAHVPCTVHHIGEGVVSWIRKKDYHLLTVGLTTYSSDERFSATHLK-HSEDWTLQIKFVQLR 252
            :|..|::||.:|.:.:..|||:|.:|.|:::|..||:.:||||.:.:.: |...|:||||:|:..
  Fly   419 MGNHAYMPCQIHRLSDKPVSWVRMRDNHIISVDETTFIADERFQSIYQEDHDYTWSLQIKYVEPS 483

  Fly   253 DAGVYECQVSTHPPTSIFLHLSVVEARAEITGPPIRYLTPGSTLRLQCRVVQNTEASEYIFWYHD 317
            |||.||||::|.|..|..:||.:|:.:.|:.|...|::..||.:.|.|.|....:..:||.|:..
  Fly   484 DAGWYECQMATEPKLSAKVHLQIVKPKTELIGDQSRFVKAGSKVALHCIVRGTLDPPKYIIWFRG 548

  Fly   318 NRMIN---------YDIDRGINVSTEPDFQSS--ELTIQRTRREHSGNFTCVASNTQPASVLVHI 371
            .:.|:         ..:||.| ..|..|.|::  .|.|...|:|.|||:||..||:...||.:|:
  Fly   549 QKKISDSDERTGWYTQLDRNI-FGTVGDNQNTIGSLIIPLVRKEDSGNYTCQPSNSVSVSVDLHV 612

  Fly   372 FKGDNPAAMYHGHVGGSTKTTQSQLH 397
            ..|:..|:........:||..:|..|
  Fly   613 LSGEYSASAIMSTAARTTKGGRSTCH 638

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr13	NP_001033956.2	V-set	180..276	CDD:284989	41/100 (41%)
		IG_like	182..262	CDD:214653	35/84 (42%)
		IG_like	285..362	CDD:214653	26/87 (30%)
		IGc2	292..361	CDD:197706	24/79 (30%)
dpr17	NP_001287297.1	IG_like	414..491	CDD:214653	32/76 (42%)
		Ig	415..507	CDD:299845	39/91 (43%)
		IG_like	521..612	CDD:214653	28/91 (31%)
		IGc2	524..605	CDD:197706	26/81 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	42	1.000	Domainoid score	I12424
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000207
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23279
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.910