DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr13 and dscamb

DIOPT Version :9

Sequence 1:	NP_001033956.2	Gene:	dpr13 / 3885598	FlyBaseID:	FBgn0034286	Length:	419	Species:	Drosophila melanogaster
Sequence 2:	XP_009289749.1	Gene:	dscamb / 386937	ZFINID:	ZDB-GENE-031118-67	Length:	2020	Species:	Danio rerio

Alignment Length:	347	Identity:	78/347 - (22%)
Similarity:	119/347 - (34%)	Gaps:	87/347 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    69 NQNLIMSQ------------SKEGEPVPVPQPYAQSAASAGGSSITSFDSTNVID---------- 111
            |:||:|..            ::.|:  ...|...|.....|...|.|..|..|:.
Zfish   367 NENLVMEGMAKSDGGAYQCFARNGK--MSTQDLVQVVLEDGTPKILSAFSEKVVSPNEPISLVCH 429

  Fly   112 --GQSQPTPT-------------HLQEAVLQTHSH-------SRIQAKDTAGPYPIPVHRPEPVE 154
              |...||.|             |..:.::.|..|       |..|..| .|.|....:......
Zfish   430 VKGTPLPTVTWTLDDDPVIKDSNHRMDRIITTEGHVLSYLNVSHTQVSD-GGVYRCTCNNSAGSV 493

  Fly   155 NHLEANNGIEGGMESLFGTPMYFGTENSTVVTTQIGATAHVPCTVHHIGEGVVSWIRKKDYHLLT 219
            :: :|...:.|....   .||    :|.|.:.   |...::.|.:.......:.|.  ||.:||.
Zfish   494 SY-QARINVRGPASI---RPM----KNVTAIA---GRDTYIHCRIIGYPYYSIKWY--KDSNLLP 545

  Fly   220 VGLTTYSSDERFSATHLKHSEDWTLQIKFVQLRDAGVYECQVSTHPPTSIFLHLSVVEARAEITG 284
                       |:........:.||::..||..|.|.|.|.|...|...|  |.||   ...:..
Zfish   546 -----------FNHRQRAFENNGTLKLSNVQNSDEGEYTCYVLVDPEKQI--HRSV---HVTVKV 594

  Fly   285 PPI------RYLTPGSTLRLQCRVVQNTEASEYIFWYHDNRMINYDIDRGINVSTEPDFQSSELT 343
            ||:      :..:.|..:.:.| ||.:.:....|.|:.|.|.||..:  |:.:. ..||.|| |.
Zfish   595 PPLIQHSDSQSASIGQRVFIPC-VVISGDLPMSITWHKDGRPINASL--GVTID-NIDFTSS-LR 654

  Fly   344 IQRTRREHSGNFTCVASNTQPA 365
            |......|:|::||:|.|...|
Zfish   655 ISNLSEIHNGSYTCIARNEAAA 676

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr13	NP_001033956.2	V-set	180..276	CDD:284989	23/95 (24%)
		IG_like	182..262	CDD:214653	17/79 (22%)
		IG_like	285..362	CDD:214653	24/82 (29%)
		IGc2	292..361	CDD:197706	22/68 (32%)
dscamb	XP_009289749.1	I-set	132..198	CDD:254352
		I-set	225..310	CDD:254352
		IGc2	239..300	CDD:197706
		IG_like	320..400	CDD:214653	6/34 (18%)
		IGc2	328..391	CDD:197706	4/23 (17%)
		IG_like	417..501	CDD:214653	14/85 (16%)
		Ig	424..498	CDD:143165	12/75 (16%)
		IG_like	511..592	CDD:214653	24/101 (24%)
		IGc2	518..576	CDD:197706	16/70 (23%)
		I-set	595..685	CDD:254352	26/87 (30%)
		Ig	612..682	CDD:143165	23/70 (33%)
		I-set	689..785	CDD:254352
		Ig7_DSCAM	706..785	CDD:143211
		IG_like	795..883	CDD:214653
		Ig	803..890	CDD:299845
		FN3	887..980	CDD:238020
		FN3	987..1084	CDD:238020
		FN3	1092..1185	CDD:238020
		FN3	1190..1279	CDD:238020
		IGc2	1302..1367	CDD:197706
		FN3	1398..1471	CDD:238020
		FN3	1485..1557	CDD:238020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810