DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr13 and wrapper

DIOPT Version :9

Sequence 1:	NP_001033956.2	Gene:	dpr13 / 3885598	FlyBaseID:	FBgn0034286	Length:	419	Species:	Drosophila melanogaster
Sequence 2:	NP_477404.1	Gene:	wrapper / 37555	FlyBaseID:	FBgn0025878	Length:	500	Species:	Drosophila melanogaster

Alignment Length:	352	Identity:	79/352 - (22%)
Similarity:	130/352 - (36%)	Gaps:	104/352 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    85 VPQPYAQSAASAGGSSITSFDSTNVIDGQSQPTPTHLQEAVLQTHSHSRIQAKDTAGPYPIPVHR 149
            ||||.           ||...:.|||  |.|....:.|..:|:      |::::.||..
  Fly   159 VPQPV-----------ITWRLNGNVI--QPQSNTGNRQSLILE------IKSRNQAGLI------ 198

  Fly   150 PEPVENHLEANNGI-EGGMESLFGTPMYFGTENS---TVVTTQIGATAHVPCTVHHIGEGVVSWI 210
                  ...|:||: |..:.::: ..:.|..|.|   .||.|::|:.||:.|.|.......|.|.
  Fly   199 ------ECVASNGVGEPAVANVY-LHVLFSPEVSIPQPVVYTKLGSRAHLECIVEAAPAATVKWF 256

  Fly   211 RKKDYHLLTVGL----TTYSSD--ERFSATHLKHSEDWTLQIKFVQLRDAGVYECQVSTHPPTSI 269
                :|.|.|.|    ||:.|:  ...|..|..::....|.:|.|:..|.|.|||:.|.
  Fly   257 ----HHGLPVALGAHSTTHESELQTNRSVDHYVNAVRHMLVVKSVRNADMGQYECRASN------ 311

  Fly   270 FLHLSVVEARAEITGPPIRYL---TPGSTLRLQCRVVQNTEASEYIFWYHDNRMINYDIDRGINV 331
              .:||.....|:||.|:..|   .||:          .:..|..:.|..::.:          .
  Fly   312 --QISVKSGSVELTGRPMPCLFKINPGT----------QSSTSHVLVWQTESLL----------P 354

  Fly   332 STEPDFQSSELTIQRTRREHSGNFTCVASNTQPASVLVHI----FKGDNPAAMYHGHV------- 385
            ..|...:..::......|:...|:|.:....|..:.|::|    ..|..||::|...|
  Fly   355 IMEFKLKFRQIPSNNVTRQVRTNWTELTIPAQATNGLIYITTYTLHGLQPASLYEVSVLARNSFG 419

  Fly   386 ------------GGSTK----TTQSQL 396
                        ||..:    :|:|:|
  Fly   420 WSDNSKIVRFATGGEVELPNYSTESEL 446

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr13	NP_001033956.2	V-set	180..276	CDD:284989	31/104 (30%)
		IG_like	182..262	CDD:214653	28/88 (32%)
		IG_like	285..362	CDD:214653	10/79 (13%)
		IGc2	292..361	CDD:197706	8/68 (12%)
wrapper	NP_477404.1	Ig	41..124	CDD:299845
		IG_like	41..118	CDD:214653
		IG_like	145..218	CDD:214653	20/90 (22%)
		Ig	147..219	CDD:299845	20/91 (22%)
		I-set	224..323	CDD:254352	32/110 (29%)
		IGc2	236..314	CDD:197706	25/89 (28%)
		FN3	339..431	CDD:238020	14/101 (14%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900