DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr13 and bdl

DIOPT Version :9

Sequence 1:	NP_001033956.2	Gene:	dpr13 / 3885598	FlyBaseID:	FBgn0034286	Length:	419	Species:	Drosophila melanogaster
Sequence 2:	NP_608822.1	Gene:	bdl / 33635	FlyBaseID:	FBgn0028482	Length:	719	Species:	Drosophila melanogaster

Alignment Length:	434	Identity:	96/434 - (22%)
Similarity:	139/434 - (32%)	Gaps:	126/434 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MPASSGLYRIKNGRVLDRLQKPAALIFIIAYIAACGI-CDHTASASPGGGKTVAATMTTPASEPS 64
            |||       |..|..  .|..:||:.::|.|....| |                   |.|:...
  Fly     1 MPA-------KRSRTF--RQSGSALLALLAIILLMNISC-------------------TSAARDH 37

  Fly    65 VRHINQNLIMSQSKEGE----------PVPVPQPYAQSAASAGGSSITSFDSTNVIDGQSQPTPT 119
            .|..|     .::|.|.          |...|.||......         |:..:.....|.|.|
  Fly    38 RRQTN-----LEAKVGSHVVFNCYIDFPFDAPIPYLVHWTK---------DNKKIFTWYEQETST 88

  Fly   120 --------HLQEAVLQTH-SHSRIQAKDTA------GPYPIPVHRPEPVENHLEANNG------I 163
                    ||    ::.| ...|.....||      |.|...|..|.  .:....|||      :
  Fly    89 SELFNGRLHL----VENHPEFGRASVNLTAIRESDQGWYHCQVSFPN--RSPSVRNNGTAYHLAV 147

  Fly   164 EGGMESLFGTPMYFGTENSTVVTTQIGATAHVPCTVHHIGEGVVSWIRKKDYHLLTVGLTTYSSD 228
            :||  ||...|    ..|.|:   :.|.||...|.:.|......||.  ||..||        .:
  Fly   148 QGG--SLIRIP----PVNQTI---REGQTAFFHCVMKHPENSQASWY--KDGVLL--------QE 193

  Fly   229 ERFSATHLKHSEDWTLQIKFVQLRDAGVYECQVSTH----PPTSIFLHLSVVEARAE-ITGPPIR 288
            .:..........|.:|.|....:.|.|.|||:|...    .....||:   ::.:|: |..||..
  Fly   194 VQDLVRRFYMGPDGSLSIDPTMMSDLGEYECKVRNSDGELQTAKAFLN---IQYKAKVIYAPPEV 255

  Fly   289 YLTPGSTLRLQCRVVQNTEASEYIFWYHDNRMI-NYDIDRGINVSTEPDFQSSELTIQRTRREHS 352
            :|..|....|.|....|..... :.|..|..:. :|::. |:...     .:..|...:....|:
  Fly   256 FLPYGQPAVLDCHFRANPPLKN-LRWEKDGLLFDSYNVP-GVFYK-----MNGSLFFAKVDENHA 313

  Fly   353 GNFTCVASN-------TQPASVLV---HIFKGDNPAAMYHGHVG 386
            |::||...|       :...||:|   .|| ...|.|:|...:|
  Fly   314 GSYTCTPYNDLGTDGPSPVISVIVLRPPIF-SVTPKAIYIQKLG 356

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr13	NP_001033956.2	V-set	180..276	CDD:284989	24/99 (24%)
		IG_like	182..262	CDD:214653	20/79 (25%)
		IG_like	285..362	CDD:214653	17/84 (20%)
		IGc2	292..361	CDD:197706	13/69 (19%)
bdl	NP_608822.1	IG_like	42..128	CDD:214653	19/103 (18%)
		Ig	43..131	CDD:299845	19/100 (19%)
		I-set	153..242	CDD:254352	25/108 (23%)
		Ig	157..242	CDD:299845	24/100 (24%)
		Ig_2	252..337	CDD:290606	19/91 (21%)
		IG_like	260..327	CDD:214653	14/73 (19%)
		I-set	341..428	CDD:254352	6/17 (35%)
		IGc2	356..419	CDD:197706	1/1 (100%)
		FN3	435..524	CDD:238020
		FN3	554..636	CDD:238020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810