DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr13 and dpr14

DIOPT Version :9

Sequence 1:	NP_001033956.2	Gene:	dpr13 / 3885598	FlyBaseID:	FBgn0034286	Length:	419	Species:	Drosophila melanogaster
Sequence 2:	NP_001245573.1	Gene:	dpr14 / 31702	FlyBaseID:	FBgn0029974	Length:	340	Species:	Drosophila melanogaster

Alignment Length:	353	Identity:	101/353 - (28%)
Similarity:	162/353 - (45%)	Gaps:	72/353 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    64 SVRHI---NQNLIMSQSKEGEPVPV-PQPYAQSAASAGGSSITSFDSTNVIDGQSQPTPTHLQEA 124
            |:.||   :.:..:.:.:.|:|... |:.:.|..:|                 ....||...:..
  Fly    15 SLHHIGSGSTSTTLKRPRAGDPFDTFPKNFWQEFSS-----------------PFTDTPEDEELE 62

  Fly   125 VLQTHSHSRIQAKDTAGPYPIPVHRPEPVENHLEANNGIEGGMESLFGTPMYFGTENSTVVTTQI 189
            |.:|.:|.         |:|                         .|..|  :.|.|   ::||:
  Fly    63 VTETTTHE---------PFP-------------------------FFADP--YTTLN---ISTQL 88

  Fly   190 GATAHVPCTVHHIGEGVVSWIRKK--DYHLLTVGLTTYSSDERFSATHLKHSEDWTLQIKFVQLR 252
            .::.::.|.|:.:....|||:|::  |..|:|.|..|||.|.|:| ...:...||.|.|:|...|
  Fly    89 SSSVYLHCRVNDLQGKTVSWMRRRGDDLTLITFGQHTYSGDSRYS-LEFEEPNDWKLLIQFANER 152

  Fly   253 DAGVYECQVSTHPPTSIFLHLSVVEARAEI-----TGPPIRYLTPGSTLRLQCRVVQNTEASEYI 312
            |.|.||||||:|||..:.::|:::....||     :..|.:|...|||:.|||.:.:....|.||
  Fly   153 DEGPYECQVSSHPPLVLLVYLTIIVPHVEILDERGSATPEKYYKAGSTIELQCVISKIPHPSSYI 217

  Fly   313 FWYHDNRMINYDIDR-GINVSTE--PDFQSSELTIQRTRREHSGNFTCVASNTQPASVLVHIFKG 374
            .|.|..|::|||..| ||:|.|:  |....|.|.|....|:.:||:||:..|....:|:||:..|
  Fly   218 TWRHGPRLLNYDTSRGGISVKTDMLPGRALSRLYIANANRQDTGNYTCMLGNEITETVVVHVLNG 282

  Fly   375 DNPAAMYHGHVGGSTKTTQSQLHMIMII 402
            :.||||.|.: |...|...|.:.::.::
  Fly   283 EEPAAMQHAN-GSRQKANASTMVVLFLV 309

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr13	NP_001033956.2	V-set	180..276	CDD:284989	37/97 (38%)
		IG_like	182..262	CDD:214653	30/81 (37%)
		IG_like	285..362	CDD:214653	31/79 (39%)
		IGc2	292..361	CDD:197706	29/71 (41%)
dpr14	NP_001245573.1	IG_like	83..163	CDD:214653	32/83 (39%)
		Ig	84..169	CDD:299845	35/85 (41%)
		IG_like	191..279	CDD:214653	34/87 (39%)
		Ig	201..274	CDD:143165	27/72 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	42	1.000	Domainoid score	I12424
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	82	1.000	Inparanoid score	I3769
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000207
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23279
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X190
	7	6.960