DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr13 and Dscaml1

DIOPT Version :9

Sequence 1:	NP_001033956.2	Gene:	dpr13 / 3885598	FlyBaseID:	FBgn0034286	Length:	419	Species:	Drosophila melanogaster
Sequence 2:	NP_001101611.1	Gene:	Dscaml1 / 315615	RGDID:	1304887	Length:	2111	Species:	Rattus norvegicus

Alignment Length:	361	Identity:	82/361 - (22%)
Similarity:	122/361 - (33%)	Gaps:	96/361 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    56 MTTPASEPSVRHI-NQNLIMSQSKEG----------EPVPVPQPYAQSAASAGGSSITSFDSTNV 109
            :..|....|:|.: |:.|::|.:::.          ......|.:|......|...|.|..|..|
  Rat   412 LVLPGEAISIRGLSNETLLISSAQKSHSGAYQCFATRKAQTAQDFAIIVLEDGTPRIVSSFSEKV 476

  Fly   110 ID------------GQSQPTPTHL--QEAVLQTHSH----------SRIQAKDTAGPY--PIPVH 148
            ::            |...||.|..  .|.|::..||          :.|...:..||.  ...|:
  Rat   477 VNPGEQFSLMCAAKGAPPPTVTWALDDEPVVRDGSHRTNQYTMSDGTTISHMNVTGPQIRDGGVY 541

  Fly   149 RPEPVENHLEANNGIEGGME-----SLFGTPMYFGTENSTVVTTQIGATAHVPCTVHHIGEGVVS 208
            |       ..|.|.: |..|     ::.|.|......|.|.|.   |....:.|.|.......:.
  Rat   542 R-------CTARNSV-GSAEYQARINVRGPPSIRAMRNITAVA---GRDTLINCRVIGYPYYSIK 595

  Fly   209 WIRK----KDYHLLTVGLTTYSSDERFSATHLKHSEDWTLQIKFVQL-RDAGVYECQVSTHPPTS 268
            |.:.    .|.|...|                  .|:.||::..||. .|.|.|.|.|...|..|
  Rat   596 WYKDALLLPDNHRQVV------------------FENGTLKLTDVQKGMDEGEYLCSVLIQPQLS 642

  Fly   269 IFLHLSVVEARAEITGPPIRYLTP--------GSTLRLQCRVVQNTEASEYIFWYHDNRMINYDI 325
            |...:.|.     :..||:  :.|        |..|.:.| ||.:.:....|.|..|.::    |
  Rat   643 ISQSVHVA-----VKVPPL--IQPFEFPPASIGQLLYIPC-VVSSGDMPIRITWRKDGQV----I 695

  Fly   326 DRGINVSTEPDFQSSELTIQRTRREHSGNFTCVASN 361
            ..|..|:.|.....|.|.|.....:|:||:||:|||
  Rat   696 ISGSGVTIESKEFMSSLQISSVSLKHNGNYTCIASN 731

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr13	NP_001033956.2	V-set	180..276	CDD:284989	23/100 (23%)
		IG_like	182..262	CDD:214653	18/84 (21%)
		IG_like	285..362	CDD:214653	26/85 (31%)
		IGc2	292..361	CDD:197706	22/76 (29%)
Dscaml1	NP_001101611.1	IG	101..173	CDD:214652
		IGc2	101..168	CDD:197706
		Ig	183..276	CDD:299845
		IG_like	195..276	CDD:214653
		I-set	291..369	CDD:254352
		IGc2	298..359	CDD:197706
		IGc2	386..447	CDD:197706	6/34 (18%)
		I-set	466..560	CDD:254352	21/101 (21%)
		Ig	466..556	CDD:299845	21/97 (22%)
		IGc2	577..635	CDD:197706	16/75 (21%)
		IG_like	665..744	CDD:214653	23/72 (32%)
		Ig	673..739	CDD:143165	21/64 (33%)
		I-set	748..843	CDD:254352
		Ig7_DSCAM	765..843	CDD:143211
		I-set	849..942	CDD:254352
		Ig	861..949	CDD:299845
		FN3	945..1039	CDD:238020
		FN3	1046..1143	CDD:238020
		fn3	1151..1237	CDD:278470
		FN3	1249..1340	CDD:238020
		IGc2	1364..1428	CDD:197706
		FN3	1442..1532	CDD:238020
		FN3	1546..1618	CDD:238020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810