DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr13 and Lrit1

DIOPT Version :9

Sequence 1:	NP_001033956.2	Gene:	dpr13 / 3885598	FlyBaseID:	FBgn0034286	Length:	419	Species:	Drosophila melanogaster
Sequence 2:	NP_647547.2	Gene:	Lrit1 / 246214	RGDID:	628607	Length:	623	Species:	Rattus norvegicus

Alignment Length:	211	Identity:	52/211 - (24%)
Similarity:	80/211 - (37%)	Gaps:	40/211 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   183 TVVTTQIGATAHVPCTVHHIGEGVVSWIRKKDYHLLTVGLTTYSSDERFSATHLKHSEDWT-LQI 246
            |.:.:.:|:|..:.|....|....:||.|.....|........|||          ...|| |.:
  Rat   261 TSIISPLGSTVLLRCGATGIPGPEMSWRRANGRPLNGTVHQEVSSD----------GSSWTLLDL 315

  Fly   247 KFVQLRDAGVYECQVSTH---PPTSIFLHLSVVEARAEITGPPIRYLTPGSTLRLQCRVVQNTEA 308
            ..|.|.|:|.|.||....   ..|.|.|.::..:...|.||      .||:   |..|..:..||
  Rat   316 PVVSLFDSGDYICQAKNFLGASETLISLIVTEPQTSTEYTG------IPGA---LWARTGEGAEA 371

  Fly   309 SEYIFWYHDNRMINY---DIDRGINVSTEPDFQS--SELTIQRTRREHSGNFTCVASNTQPASVL 368
            :.|     :|:::..   .:...:.::|:|...|  .||.:|..:.:..|.|:...|..|... :
  Rat   372 AAY-----NNKLVARHVPHVPEPVALATKPSVPSIKEELPLQNFQMDVPGEFSREPSEHQETQ-M 430

  Fly   369 VHIFK--GDNPAAMYH 382
            |...|  ||.    ||
  Rat   431 VRSLKVVGDT----YH 442

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr13	NP_001033956.2	V-set	180..276	CDD:284989	25/96 (26%)
		IG_like	182..262	CDD:214653	22/79 (28%)
		IG_like	285..362	CDD:214653	17/81 (21%)
		IGc2	292..361	CDD:197706	16/73 (22%)
Lrit1	NP_647547.2	LRRNT	23..61	CDD:214470
		LRR 1	60..81
		LRR_8	63..143	CDD:290566
		leucine-rich repeat	64..84	CDD:275378
		LRR 2	84..105
		leucine-rich repeat	85..132	CDD:275378
		LRR 3	108..128
		LRR_8	131..>176	CDD:290566
		LRR_4	131..172	CDD:289563
		LRR 4	132..153
		leucine-rich repeat	133..156	CDD:275378
		LRR 5	156..177
		leucine-rich repeat	157..180	CDD:275378
		leucine-rich repeat	181..205	CDD:275378
		TPKR_C2	201..>240	CDD:301599
		Ig	257..345	CDD:299845	25/93 (27%)
		IG_like	267..345	CDD:214653	24/87 (28%)
		FN3	431..501	CDD:214495	6/16 (38%)
		LRR 6	525..548
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900