DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr13 and igcm-2

DIOPT Version :9

Sequence 1:	NP_001033956.2	Gene:	dpr13 / 3885598	FlyBaseID:	FBgn0034286	Length:	419	Species:	Drosophila melanogaster
Sequence 2:	NP_001362087.1	Gene:	igcm-2 / 180913	WormBaseID:	WBGene00020130	Length:	802	Species:	Caenorhabditis elegans

Alignment Length:	406	Identity:	91/406 - (22%)
Similarity:	131/406 - (32%)	Gaps:	147/406 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 HTASASPGGGKTVAATMTTPASEPSVRHINQNLIMSQSKEGEPVPVPQPYAQSAASAGGSSITSF 104
            :|..|....|:|.::|.......|.                ||:...|| .|:.||...:::
Worm   278 YTCEAKNSAGETTSSTAYLHVFYPP----------------EPLSSHQP-VQTVASGRNTTV--- 322

  Fly   105 DSTNVIDGQSQPTPTHLQEA----VLQTHSHSRI---------------QAKDTAGPYPIPVHRP 150
             |.:||   :.||||....:    .|.|.:.|.|               ||.:.||...|
Worm   323 -SCDVI---ANPTPTSYTWSKNGHYLPTQASSHIIISYAKPGDGGIYGCQADNIAGKGSI----- 378

  Fly   151 EPVENHLEANNGIEGGMESLFGTPMYFGTENSTVVTTQIGATAHVPCTVHHIGEG----VVSWIR 211
              ||.||            :...|..|.....:.:..::|....:||.    |.|    :|.|||
Worm   379 --VETHL------------IVAEPPVFTVAPPSEIKVRLGDQVSIPCQ----GFGDPMPIVYWIR 425

  Fly   212 KKDYHLLTVGLTTYSSDERFSATHLKHSEDWTLQIKFVQLRDAGVYECQVSTHPPTSIFLHLSV- 275
            .|                       |.....||..|.|:..|.|.|||.|:....|     :|.
Worm   426 DK-----------------------KRINQSTLTFKKVEHLDHGAYECVVANSVET-----ISTR 462

  Fly   276 VEARAEITGPPIRYLTPGSTLRLQCRVVQNTEASEYIFW---YHDNRMINYDIDRGINVSTEPDF 337
            |....|||.|.:     .|:::..|.    ..:|..|.|   |      |...|:...|..:.|
Worm   463 VMLLVEITKPQM-----ASSIKFTCL----NSSSMRISWTPGY------NGGFDQTFAVHAQND- 511

  Fly   338 QSSELTIQRTRREHSGNFTCVASNTQPASVLVHIFKGDNPAAMYHGHV-----GGSTKTTQ---- 393
                :|:|.|..:.|.|.|          :|.|:    .|...|...:     .|||.:|.
Worm   512 ----VTLQWTSIKTSLNET----------ILDHL----EPFVSYRVSIESVNAKGSTNSTTYNRR 558

  Fly   394 --SQLHMIMIIIASGY 407
              :.||....:...||
Worm   559 SCTSLHAPDKLYFCGY 574

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr13	NP_001033956.2	V-set	180..276	CDD:284989	23/100 (23%)
		IG_like	182..262	CDD:214653	20/83 (24%)
		IG_like	285..362	CDD:214653	17/79 (22%)
		IGc2	292..361	CDD:197706	16/71 (23%)
igcm-2	NP_001362087.1	IG_like	23..101	CDD:214653
		Ig	124..200	CDD:386229
		IG_like	214..298	CDD:214653	5/19 (26%)
		Ig_3	309..371	CDD:372822	18/69 (26%)
		Ig	389..467	CDD:386229	25/109 (23%)
		FN3	476..548	CDD:238020	20/100 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900