DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr13 and rig-4

DIOPT Version :9

Sequence 1:	NP_001033956.2	Gene:	dpr13 / 3885598	FlyBaseID:	FBgn0034286	Length:	419	Species:	Drosophila melanogaster
Sequence 2:	NP_501339.2	Gene:	rig-4 / 177597	WormBaseID:	WBGene00004371	Length:	2325	Species:	Caenorhabditis elegans

Alignment Length:	237	Identity:	51/237 - (21%)
Similarity:	90/237 - (37%)	Gaps:	81/237 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   160 NNGIEGGMESLFGTPMYFGTENSTVVTTQIGATAHVPCTVH-HIGEGVVSWIRKKDYHL------ 217
            :||:...:::.... :||.|:.:.:.:|       :|   | .|.:.|.|:..|.|..:
Worm   212 DNGLSPSLQNTLSI-VYFPTDRTIIEST-------LP---HDEIFDCVTSFGSKDDVRIRWFLNG 265

  Fly   218 -----LTVGLTTYSSDERF------SATHLKHSEDWTLQIKFVQLRDAGVYECQVS-----THPP 266
                 ..||:||..::.|.      |.|..:|.                 .||:..     |...
Worm   266 QQISGSEVGMTTTLNNRRLIISNPSSFTRGEHK-----------------LECRADAAMGRTSDQ 313

  Fly   267 TSIFLHLSVVEARAEITGPPIRYL------TPGSTLRLQCRVVQNTEASEYIFWYHDNRMINYDI 325
            .|.::..        |:.|.::.|      |.||:|.|:|.|  ..::|..|.||.:
Worm   314 KSAYMTF--------ISRPILKDLPNEIQKTVGSSLSLKCSV--KKKSSMDIKWYKN-------- 360

  Fly   326 DRGINVSTEPDFQSSELTIQRTRREHSGNFTCVASNTQPASV 367
              |:.::|    |..:|||.|.:::..|.:.|.|:|...|.:
Worm   361 --GLMMTT----QRGKLTIDRIKQDDFGLYQCEATNAAGADL 396

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr13	NP_001033956.2	V-set	180..276	CDD:284989	20/118 (17%)
		IG_like	182..262	CDD:214653	18/97 (19%)
		IG_like	285..362	CDD:214653	23/82 (28%)
		IGc2	292..361	CDD:197706	20/68 (29%)
rig-4	NP_501339.2	IG_like	330..402	CDD:214653	23/83 (28%)
		IGc2	338..393	CDD:197706	21/70 (30%)
		I-set	459..543	CDD:254352
		IGc2	478..534	CDD:197706
		IG_like	553..639	CDD:214653
		Ig	564..635	CDD:143165
		FN3	643..747	CDD:238020
		FN3	756..850	CDD:238020
		FN3	858..954	CDD:238020
		FN3	959..1042	CDD:238020
		FN3	1057..1151	CDD:238020
		FN3	1156..1251	CDD:238020
		FN3	1258..1356	CDD:238020
		FN3	1361..1453	CDD:238020
		FN3	1464..1560	CDD:238020
		FN3	1572..1664	CDD:238020
		FN3	1679..1764	CDD:238020
		FN3	1774..1858	CDD:238020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810