DRSC/TRiP Functional Genomics Resources

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Protein Alignment dpr13 and negr1

DIOPT Version :9

Sequence 1:NP_001033956.2 Gene:dpr13 / 3885598 FlyBaseID:FBgn0034286 Length:419 Species:Drosophila melanogaster
Sequence 2:XP_031755650.1 Gene:negr1 / 100127726 XenbaseID:XB-GENE-987949 Length:388 Species:Xenopus tropicalis


Alignment Length:269 Identity:62/269 - (23%)
Similarity:95/269 - (35%) Gaps:102/269 - (37%)


- Green bases have known domain annotations that are detailed below.


  Fly   190 GATAHVPCTVHHIGEGVVSWIRKKDYHLLTVGLTTYSSDERFS-ATHLKHSEDWTLQIKFVQLRD 253
            |.||.:.|.:.. |....:|:.:..  ::..|...:|.|.|.| ||..|  ::::|:|:.|.:.|
 Frog    54 GETAMLRCFLEE-GASKGAWLNRSS--IIFAGGDKWSVDPRVSIATSSK--QEYSLRIQKVDVSD 113

  Fly   254 AGVYECQVST-HPPTSIFLHLSV--------------------VEARAEITGPP-----IRYLTP 292
            .|.|.|.|.| |.|.::.:||:|                    |......||.|     .|:::|
 Frog   114 DGPYTCSVQTEHSPRTLQVHLTV
HVSPKIYDISSDMTVNEGTNVSLICLATGKPEPSISWRHISP 178

  Fly   293 -----GSTLRLQCRVVQNTEASEY----------------------------------------- 311
                 ||...|....:...:|.:|                                         
 Frog   179 SAKQFGSGQYLDIYGITRDQAGDYECSAENDVSFPDVKKVKVTVNFAPTILEITPTGVSLGRTGL 243

  Fly   312 -----------IF-WYHDNRMINYDIDRGI---NVSTEPDFQSSELTIQRTRREHSGNFTCVASN 361
                       :| ||...:.:. :..|||   |.:|.     |.||:.....||.||:||||.|
 Frog   244 IRCETAAVPAPVFEWYKGEKKLT-NGQRGIRIQNYNTR-----SILTVSNVTEEHFGNYTCVAVN 302

  Fly   362 ---TQPASV 367
               |..||:
 Frog   303 KLGTSNASL 311

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dpr13NP_001033956.2 V-set 180..276 CDD:284989 28/107 (26%)
IG_like 182..262 CDD:214653 21/72 (29%)
IG_like 285..362 CDD:214653 28/145 (19%)
IGc2 292..361 CDD:197706 25/129 (19%)
negr1XP_031755650.1 Ig 44..136 CDD:416386 27/86 (31%)
FR1 44..62 CDD:409353 3/7 (43%)
Ig strand A' 47..53 CDD:409353
Ig strand B 55..63 CDD:409353 3/7 (43%)
CDR1 63..68 CDD:409353 1/5 (20%)
FR2 69..75 CDD:409353 1/5 (20%)
Ig strand C 69..74 CDD:409353 1/4 (25%)
CDR2 76..87 CDD:409353 1/12 (8%)
Ig strand C' 78..82 CDD:409353 0/3 (0%)
Ig strand C' 84..87 CDD:409353 0/2 (0%)
FR3 88..122 CDD:409353 13/35 (37%)
Ig strand D 91..98 CDD:409353 4/6 (67%)
Ig strand E 101..107 CDD:409353 1/5 (20%)
Ig strand F 114..122 CDD:409353 3/7 (43%)
CDR3 123..127 CDD:409353 2/3 (67%)
Ig strand G 127..136 CDD:409353 3/8 (38%)
FR4 129..136 CDD:409353 2/6 (33%)
Ig_3 140..208 CDD:404760 11/67 (16%)
Ig strand A' 146..151 CDD:409353 0/4 (0%)
Ig strand B 157..164 CDD:409353 1/6 (17%)
Ig strand C 170..175 CDD:409353 0/4 (0%)
Ig strand C' 177..179 CDD:409353 0/1 (0%)
Ig strand E 187..193 CDD:409353 1/5 (20%)
Ig strand F 200..207 CDD:409353 1/6 (17%)
Ig strand G 214..222 CDD:409353 0/7 (0%)
Ig_3 226..302 CDD:404760 19/81 (23%)
putative Ig strand A 226..232 CDD:409353 0/5 (0%)
Ig strand B 242..246 CDD:409353 0/3 (0%)
Ig strand C 255..259 CDD:409353 1/3 (33%)
Ig strand E 281..285 CDD:409353 2/3 (67%)
Ig strand F 295..300 CDD:409353 3/4 (75%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 1 1.000 46 1.000 Domainoid score I11916
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.000

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