DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33460 and CG42694

DIOPT Version :9

Sequence 1:	NP_001033949.1	Gene:	CG33460 / 3885588	FlyBaseID:	FBgn0053460	Length:	275	Species:	Drosophila melanogaster
Sequence 2:	NP_001188994.1	Gene:	CG42694 / 10178792	FlyBaseID:	FBgn0261584	Length:	512	Species:	Drosophila melanogaster

Alignment Length:	289	Identity:	81/289 - (28%)
Similarity:	125/289 - (43%)	Gaps:	50/289 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 MLVIYSDSVSANYLYEQCGL-MREEFSTSL----GPWTALLHTDGSIFCAGTLITDVFILTAASC 73
            ||.:....|::.:|.:.||. :..:..|.|    ..|.|.:.....:.|:|:||:..|:|:||.|
  Fly    10 MLTVLQSHVNSKFLDDYCGAPISNQSITKLRQPQAGWLAHISNGTHVLCSGSLISKQFVLSAAQC 74

  Fly    74 IRPNA-VKVRLGEFGRYPNELPEDHLVHYFLMYRLFN-------NESLANNIGLLKLTKRVQITD 130
            |..:. :.|:||    ..|.....|      .|.:.|       .:.|..:||||||::.|...|
  Fly    75 IDVHGKLFVQLG----VSNATKSPH------WYTVSNVVIPSHSGKRLQRDIGLLKLSQSVDYND 129

  Fly   131 YIMPVCIVLNPQNQQLSTM--RFIGNAWMEDSNVSLTKELRPIVIQSKPKMCTNLDLY-----TQ 188
            ::.|:||.||.....:..:  .|..:||:     |..|..:.||:....:....|:|.     .:
  Fly   130 FVYPICIALNTNTLDMVKILQNFTTSAWL-----SKNKNPQTIVLSQLSRDRCKLNLSGNVTPKE 189

  Fly   189 FCAGHQGNLRSCDGLTGSAL----IQNSRYMNKYRHIQFGI-ATVNDMD-CEESQGYTDVLKFYW 247
            .||.......||...:||||    ||.|   |..|.:.||| ..||... |.|...|.||.:...
  Fly   190 ICAASLQRNNSCFIDSGSALTQPIIQGS---NIVREMLFGIRGYVNGRSWCSEPAIYIDVAECVG 251

  Fly   248 WIQDVVSLFNHYSTNESYI----VNDYIK 272
            ||:.||..::  .|:...:    ||.::|
  Fly   252 WIETVVQQYD--GTDSRAVATPEVNQHLK 278

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33460	NP_001033949.1	Tryp_SPc	44..252	CDD:304450	67/228 (29%)
CG33460	NP_001033949.1	Tryp_SPc	44..249	CDD:214473	65/225 (29%)
CG42694	NP_001188994.1	Tryp_SPc	46..256	CDD:304450	67/227 (30%)
		Tryp_SPc	46..253	CDD:214473	65/224 (29%)
		Tryp_SPc	319..505	CDD:304450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45463384
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000404
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	3.030