DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33465 and tmprss4a

DIOPT Version :9

Sequence 1:	NP_001033950.2	Gene:	CG33465 / 3885587	FlyBaseID:	FBgn0053465	Length:	488	Species:	Drosophila melanogaster
Sequence 2:	XP_005157547.1	Gene:	tmprss4a / 777630	ZFINID:	ZDB-GENE-061103-631	Length:	458	Species:	Danio rerio

Alignment Length:	254	Identity:	62/254 - (24%)
Similarity:	104/254 - (40%)	Gaps:	61/254 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 PWMASIYKNNQFICDGTLVHKLFVLTAASCISKD-----SQLYVLFGMYNQYRDASQFFNNEQYG 105
            ||..|:..:.|..|.|:||...:|:|||.|.:.|     |:..|:.|:.......|.:
Zfish   236 PWQVSLQYSGQHTCGGSLVTPNWVVTAAHCFNGDGRKALSRWTVVSGITYLSSTPSSY------- 293

  Fly   106 VAVALQHSNFRPNNGVNDIGLLRLYGEVTHYAHIRPICIILDHV-VKSAPFERFEGF---GW--- 163
            |...:.:||::|.....||.:::|...:|.....||:|:...:: :|..     :|.   ||
Zfish   294 VKEIIVNSNYKPAESDFDITMIKLQSPITLSESRRPVCLPPQNLGLKGG-----DGLVVTGWGHM 353

  Fly   164 QQQGTEASSQVRQ--------------TVYLSQKKPFECHRNGQLLPINEGQFCAGNRDRSF--C 212
            .::|...||.:::              |||.|.              |.....|||......  |
Zfish   354 AEKGGSLSSMLQKAQIQVIDSAQCSSPTVYGSS--------------ITPRMICAGVMAGGVDAC 404

  Fly   213 RSNSGSPLTADFTYGVKNITVQVGLVSYGSELCSP--TSVYTDVVAFKDWIYNTVRNFE 269
            :.:||.||.     .:.:..|.||:||:|.....|  ..|||:|....||.::.::.::
Zfish   405 QGDSGGPLV-----HLADRWVLVGVVSWGVGCARPGFPGVYTNVDQMLDWAHSVMQTYK 458

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33465	NP_001033950.2	Tryp_SPc	46..264	CDD:238113	62/247 (25%)
		Tryp_SPc	46..261	CDD:214473	61/244 (25%)
		Tryp_SPc	293..484	CDD:304450
		Tryp_SPc	293..481	CDD:214473
tmprss4a	XP_005157547.1	LDLa	74..105	CDD:238060
		SRCR_2	121..218	CDD:295335
		Tryp_SPc	223..449	CDD:214473	60/243 (25%)
		Tryp_SPc	224..449	CDD:238113	60/243 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910