DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33465 and Prss22

DIOPT Version :9

Sequence 1:	NP_001033950.2	Gene:	CG33465 / 3885587	FlyBaseID:	FBgn0053465	Length:	488	Species:	Drosophila melanogaster
Sequence 2:	XP_006524968.4	Gene:	Prss22 / 70835	MGIID:	1918085	Length:	365	Species:	Mus musculus

Alignment Length:	297	Identity:	78/297 - (26%)
Similarity:	123/297 - (41%)	Gaps:	51/297 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 LIGLVLCQGLAQL------LDKKCHDPKTSENINFNHGATETA-PWMASIYKNNQFICDGTLVHK 66
            ||.|||....|.:      :...|..|:....|.....:.:.. ||:.||.||....|.|:|:..
Mouse    76 LILLVLLTSTAPISAATIRVSPDCGKPQQLNRIVGGEDSMDAQWPWIVSILKNGSHHCAGSLLTN 140

  Fly    67 LFVLTAASC----ISKDSQLYVLFGMYNQYRDASQFFNNEQYGVAVALQHSNFRPNNGVN-DIGL 126
            .:|:|||.|    :.|.|...||.|   .::..|....:::.|:|..|.|..:....|.: ||.|
Mouse   141 RWVVTAAHCFKSNMDKPSLFSVLLG---AWKLGSPGPRSQKVGIAWVLPHPRYSWKEGTHADIAL 202

  Fly   127 LRLYGEVTHYAHIRPICIILDHVVKSAPFER--FEGFGWQQQGTE--------------ASSQVR 175
            :||...:.....|.||| :.|..|:..|...  ..|:|..|.|..              ..|::.
Mouse   203 VRLEHSIQFSERILPIC-LPDSSVRLPPKTDCWIAGWGSIQDGVPLPHPQTLQKLKVPIIDSELC 266

  Fly   176 QTVYLSQKKPFECHRNGQLLPINEGQFCAG--NRDRSFCRSNSGSPLTADFTYGVKNITVQVGLV 238
            :::|         .|......|.||..|||  ..:|..|..:||.||...    |.:..:..|::
Mouse   267 KSLY---------WRGAGQEAITEGMLCAGYLEGERDACLGDSGGPLMCQ----VDDHWLLTGII 318

  Fly   239 SYGSELCSPTS---VYTDVVAFKDWIYNTVRNFETKG 272
            |:| |.|:..:   |||.::|.:.|:...|:..:.:|
Mouse   319 SWG-EGCAERNRPGVYTSLLAHRSWVQRIVQGVQLRG 354

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33465	NP_001033950.2	Tryp_SPc	46..264	CDD:238113	67/243 (28%)
		Tryp_SPc	46..261	CDD:214473	66/240 (28%)
		Tryp_SPc	293..484	CDD:304450
		Tryp_SPc	293..481	CDD:214473
Prss22	XP_006524968.4	Tryp_SPc	108..346	CDD:238113	68/255 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910