DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG33465 and Ctrb1

DIOPT Version :9

Sequence 1:	NP_001033950.2	Gene:	CG33465 / 3885587	FlyBaseID:	FBgn0053465	Length:	488	Species:	Drosophila melanogaster
Sequence 2:	NP_079859.2	Gene:	Ctrb1 / 66473	MGIID:	88559	Length:	263	Species:	Mus musculus

Alignment Length:	234	Identity:	58/234 - (24%)
Similarity:	92/234 - (39%)	Gaps:	41/234 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 PWMASIYKNNQF-ICDGTLVHKLFVLTAASCISKDSQLYVLFGMYNQYRDASQFFNNEQYGVAVA 109
            ||..|:.....| .|.|:|:.:.:|:|||.|..|.:.: |:.|.::|..|..   |.:...:|..
Mouse    46 PWQVSLQDRTGFHFCGGSLISENWVVTAAHCGVKTTDV-VVAGEFDQGSDEE---NVQVLKIAQV 106

  Fly   110 LQHSNFRPNNGVNDIGLLRLYGEVTHYAHIRPICI-ILDHVVKSAPFERFEGFGWQQQGTEASSQ 173
            .::..|......|||.||:|.........:..:|: .:|....:.......|:|
Mouse   107 FKNPKFNSFTVRNDITLLKLATPAQFSETVSAVCLPTVDDDFPAGTLCATTGWG----------- 160

  Fly   174 VRQTVYLSQKKPFECHRNGQLLP--------------INEGQFCAGNRDRSFCRSNSGSPLTADF 224
              :|.|.:.|.|.:..:  ..||              |.:...|||....|.|..:||.||...
Mouse   161 --KTKYNALKTPDKLQQ--AALPIVSEAKCKESWGSKITDVMICAGASGVSSCMGDSGGPLVCQ- 220

  Fly   225 TYGVKNITVQVGLVSYGSELCSPT--SVYTDVVAFKDWI 261
               ...:....|:||:||..||.:  :||..|.|...|:
Mouse   221 ---KDGVWTLAGIVSWGSGFCSTSTPAVYARVTALMPWV 256

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33465	NP_001033950.2	Tryp_SPc	46..264	CDD:238113	58/234 (25%)
		Tryp_SPc	46..261	CDD:214473	57/232 (25%)
		Tryp_SPc	293..484	CDD:304450
		Tryp_SPc	293..481	CDD:214473
Ctrb1	NP_079859.2	Tryp_SPc	33..256	CDD:214473	57/232 (25%)
Ctrb1	NP_079859.2	Tryp_SPc	34..259	CDD:238113	58/234 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910