DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33465 and c1s

DIOPT Version :9

Sequence 1:	NP_001033950.2	Gene:	CG33465 / 3885587	FlyBaseID:	FBgn0053465	Length:	488	Species:	Drosophila melanogaster
Sequence 2:	XP_002941253.2	Gene:	c1s / 613055	XenbaseID:	XB-GENE-995410	Length:	691	Species:	Xenopus tropicalis

Alignment Length:	263	Identity:	65/263 - (24%)
Similarity:	106/263 - (40%)	Gaps:	59/263 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 PWMASIYKNNQF----ICDGTLVHKLFVLTAASCISKDSQLY-VLFGMYNQYRDASQFFNN---- 101
            |||.      ||    :..|:|:...:|||||..::|  ::: .:||      ...:||.|
Frog   449 PWMI------QFTDIELGGGSLISDRWVLTAAHVVNK--KIFPTMFG------GVMKFFPNTNLQ 499

  Fly   102 ---EQYGVAVALQHSNFRPN-------NGVNDIGLLRLYGEVTHYAHIRPICI-------ILDHV 149
               ::......:.|..::.|       |..|||.|::|..:|...:.|.|||:       :::.|
Frog   500 SQEKRLQAKKIIIHPLYQDNEDTEGQSNFDNDIALVQLTKKVKLGSCISPICLPRRGLAPVVNEV 564

  Fly   150 VKSAPFERFEGFGWQQQGTEASSQVRQTVYLSQKKPFECHR----NGQLLPINEGQFCAGNR-DR 209
            ...|        ||.:.....|:...|...:|.....:|.:    .|...|   ...|||:. .:
Frog   565 ATIA--------GWGKTEKRESAVNLQFASISLSSMDKCKKATGGKGYFTP---NMLCAGSDVGK 618

  Fly   210 SFCRSNSGSPLTADFTYGVKNITV-QVGLVSYGSELCSPTSVYTDVVAFKDWIYNTVRNFETKGD 273
            ..|..:||.||.  ||....:..: ..|:||:|...|....:||.|..:.|||..|:...|.:..
Frog   619 DSCNGDSGGPLM--FTDPQDSSKMYMAGIVSWGPRDCGTYGLYTKVDNYLDWIEETIAAVEREEQ 681

  Fly   274 QVV 276
            :.|
Frog   682 EEV 684

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33465	NP_001033950.2	Tryp_SPc	46..264	CDD:238113	62/249 (25%)
		Tryp_SPc	46..261	CDD:214473	60/246 (24%)
		Tryp_SPc	293..484	CDD:304450
		Tryp_SPc	293..481	CDD:214473
c1s	XP_002941253.2	CUB	21..131	CDD:238001
		FXa_inhibition	145..173	CDD:405372
		CUB	177..288	CDD:238001
		PHA02927	301..>436	CDD:222943
		Tryp_SPc	436..669	CDD:214473	60/246 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910