DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG33465 and si:dkeyp-93a5.3

DIOPT Version :9

Sequence 1:	NP_001033950.2	Gene:	CG33465 / 3885587	FlyBaseID:	FBgn0053465	Length:	488	Species:	Drosophila melanogaster
Sequence 2:	XP_021326347.1	Gene:	si:dkeyp-93a5.3 / 571565	ZFINID:	ZDB-GENE-131127-100	Length:	328	Species:	Danio rerio

Alignment Length:	267	Identity:	69/267 - (25%)
Similarity:	107/267 - (40%)	Gaps:	50/267 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 DPKTSENINFNHGATETAPWMASIYKNNQFICDGTLVHKLFVLTAASCI--SKDSQLYVLFGMYN 90
            :|:....:|..|||.   |||.|:.......|.|:|::..:|||||.||  ...|.:.|..|.:.
Zfish    33 NPRIVGGVNATHGAW---PWMVSLQGRYGHFCGGSLINNQWVLTAAHCIVDQTPSSIIVYLGKWR 94

  Fly    91 QY-RDASQFFNNEQYGVAVALQHSNFRPNNGVNDIGLLRLYGEVTHYAHIRPICIILDHVVKSAP 154
            .| .|.    |:....:...:.|.::......|||.||:|...|.:..:|:|||:    ..:::.
Zfish    95 SYVADV----NSISRTIRHIIPHPSYSNITKDNDIALLQLTSTVQYTDYIKPICL----ADENSN 151

  Fly   155 FERFEG---FGWQQQGTEASSQVRQTVYLSQKKPFE-------------------CHRNGQLLPI 197
            |.|...   .||...|...:..:|....:|...|..                   ||  |::.|
Zfish   152 FPRGTNSWVAGWGDIGVLGTGGIRGRTTVSVPLPHPGILQEAELKVYSNADCNNICH--GRITP- 213

  Fly   198 NEGQFCAGNR--DRSFCRSNSGSPLTADFTYGVKNITVQVGLVSYGSELCSPT--SVYTDVVAFK 258
              ...|||.|  .::....:||.||....     ::.||.|::|:|.....|.  .|:..|..:|
Zfish   214 --NMICAGTRPGGKATFSGDSGGPLMTKC-----SVWVQAGVLSHGYGCAQPNLPEVFIRVSEYK 271

  Fly   259 DWIYNTV 265
            .||...|
Zfish   272 QWITGNV 278

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33465	NP_001033950.2	Tryp_SPc	46..264	CDD:238113	63/246 (26%)
		Tryp_SPc	46..261	CDD:214473	61/243 (25%)
		Tryp_SPc	293..484	CDD:304450
		Tryp_SPc	293..481	CDD:214473
si:dkeyp-93a5.3	XP_021326347.1	Tryp_SPc	36..274	CDD:238113	65/258 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910