DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG33465 and AgaP_AGAP005686

DIOPT Version :9

Sequence 1:	NP_001033950.2	Gene:	CG33465 / 3885587	FlyBaseID:	FBgn0053465	Length:	488	Species:	Drosophila melanogaster
Sequence 2:	XP_001688706.1	Gene:	AgaP_AGAP005686 / 5667393	VectorBaseID:	AGAP005686	Length:	297	Species:	Anopheles gambiae

Alignment Length:	306	Identity:	73/306 - (23%)
Similarity:	115/306 - (37%)	Gaps:	62/306 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 RVLSLALIGLVLCQGLAQLLDKKCHDPKTSENINFNHGATETAPWMASIYKN------------- 54
            |...||::.|.:....|:.:|......:..|  .|:|......|.|.: |:|
Mosquito     2 RSFVLAVVCLAVAAARAEQIDIDWSKVRPVE--EFDHYWARLPPEMQA-YRNETSTDRITNGQEA 63

  Fly    55 --NQF---------------ICDGTLVHKLFVLTAASCIS-----KDSQLYVLFGMYNQ-YRDAS 96
              .||               :|..:::.:.|:||||.|||     ..|....:.|..|: ..:.|
Mosquito    64 LPGQFPYQVALLSDFPEGTALCGASVLTRNFLLTAAHCISGTGNALSSGGIAIMGAQNRMIVELS 128

  Fly    97 QFFNNEQYGVAVALQHSNFRPNNGVNDIGLLRLYGEVTHYAHIRPICIILDHVVKSAPFERFEGF 161
            |  ...::..:...:|..:...:..||:.|:.|...:|..:.::||     .:.......:|.||
Mosquito   129 Q--QRIRFSTSGIRRHPGYDATSLRNDVALVLLNSRITFTSRVQPI-----RLPARTDTRQFGGF 186

  Fly   162 GWQQQG---TEASSQVRQTVYLSQKKPF----ECHRN-GQLLPINEGQFCAGNRDRSFCRSNSGS 218
            .....|   |..|||...........|.    ||..: |..|..::......:..||.|..:||.
Mosquito   187 TGTVSGFGRTTDSSQATSATLRFTSNPVLTNAECITSWGFGLAQSQNVCLKASGGRSACNGDSGG 251

  Fly   219 PLTADFTYGVKNITVQVGLVSYGSEL-CSP--TSVYTDVVAFKDWI 261
            |||.|     .|..:|:|:||:.|.. |:.  .|||..|..|..||
Mosquito   252 PLTVD-----SNGVLQIGVVSFVSAAGCASGRPSVYARVTYFLPWI 292

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33465	NP_001033950.2	Tryp_SPc	46..264	CDD:238113	64/263 (24%)
		Tryp_SPc	46..261	CDD:214473	62/261 (24%)
		Tryp_SPc	293..484	CDD:304450
		Tryp_SPc	293..481	CDD:214473
AgaP_AGAP005686	XP_001688706.1	Tryp_SPc	56..292	CDD:214473	58/247 (23%)
AgaP_AGAP005686	XP_001688706.1	Tryp_SPc	57..295	CDD:238113	60/248 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910