DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33465 and PRSS1

DIOPT Version :9

Sequence 1:	NP_001033950.2	Gene:	CG33465 / 3885587	FlyBaseID:	FBgn0053465	Length:	488	Species:	Drosophila melanogaster
Sequence 2:	XP_011514713.1	Gene:	PRSS1 / 5644	HGNCID:	9475	Length:	472	Species:	Homo sapiens

Alignment Length:	248	Identity:	64/248 - (25%)
Similarity:	98/248 - (39%)	Gaps:	64/248 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 TAPWMASIYKNNQFICDGTLVHKLFVLTAASCISKDSQLYVLFGMYNQYRDASQFFNNEQY-GVA 107
            :.|:..|:.....| |.|:|:::.:|::|..|..  |::.|..|.:|    ......|||: ..|
Human   259 SVPYQVSLNSGYHF-CGGSLINEQWVVSAGHCYK--SRIQVRLGEHN----IEVLEGNEQFINAA 316

  Fly   108 VALQHSNFRPNNGVNDIGLLRLYGEVTHYAHIRPI------------CIILDHVVKSAPFERFEG 160
            ..::|..:......|||.|::|.......|.:..|            |:|
Human   317 KIIRHPQYDRKTLNNDIMLIKLSSRAVINARVSTISLPTAPPATGTKCLI--------------- 366

  Fly   161 FGWQQQGTEASS--------QVRQTVYLSQKKPFECHRNGQLLPINEGQFCAG--NRDRSFCRSN 215
            .||   |..|||        |......|||.| .|....|:   |....||.|  ...:..|:.:
Human   367 SGW---GNTASSGADYPDELQCLDAPVLSQAK-CEASYPGK---ITSNMFCVGFLEGGKDSCQGD 424

  Fly   216 SGSPLTADFTYGVKNITVQVGLVSYGSELCSPTS---VYTDVVAFKDWIYNTV 265
            ||.|:       |.|..:| |:||:| :.|:..:   |||.|..:..||.||:
Human   425 SGGPV-------VCNGQLQ-GVVSWG-DGCAQKNKPGVYTKVYNYVKWIKNTI 468

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33465	NP_001033950.2	Tryp_SPc	46..264	CDD:238113	62/243 (26%)
		Tryp_SPc	46..261	CDD:214473	60/240 (25%)
		Tryp_SPc	293..484	CDD:304450
		Tryp_SPc	293..481	CDD:214473
PRSS1	XP_011514713.1	Ig	19..119	CDD:299845
		IG_like	29..113	CDD:214653
		Tryp_SPc	248..464	CDD:214473	60/242 (25%)
		Tryp_SPc	249..467	CDD:238113	62/245 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910