DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG33465 and CG10764

DIOPT Version :9

Sequence 1:	NP_001033950.2	Gene:	CG33465 / 3885587	FlyBaseID:	FBgn0053465	Length:	488	Species:	Drosophila melanogaster
Sequence 2:	NP_611213.2	Gene:	CG10764 / 36962	FlyBaseID:	FBgn0034221	Length:	523	Species:	Drosophila melanogaster

Alignment Length:	551	Identity:	150/551 - (27%)
Similarity:	249/551 - (45%)	Gaps:	99/551 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSRVLSLALIGLV-LC---QGLAQLLDKKC---HDPKTSENINFNHGATETAPWMASIYKNNQFI 58
            |..::|:||:.|: ||   ....:.|:..|   ..||.|..   :..|...:.|||:|:.::.|.
  Fly     1 MRSLVSVALLSLLTLCVTENEHFKFLETPCGISTRPKISGG---DDAAEPNSIWMAAIFNSSDFQ 62

  Fly    59 CDGTLVHKLFVLTAASCISKDSQLYVLFGMYNQYRDASQFFNNEQYGVAVALQ---HSNFRPNNG 120
            |.||::|..|||:||.|:.:...|||..|..|         .||...|...:.   |.:|..:..
  Fly    63 CGGTIIHMRFVLSAAHCLVRGYDLYVRLGARN---------INEPAAVHTVINVFVHHDFIASEY 118

  Fly   121 VNDIGLLRLYGEVTHYAHIRPICIILDHVVKSA--PFERFEGFGWQQQGTEASSQVRQTVYLSQK 183
            .||||||:|...:.:...::||||.||..:|.:  ..:.|...||..:..:.|..: ||:||...
  Fly   119 RNDIGLLQLSESIVYTVRVQPICIFLDPALKGSVEKLKTFRALGWGNRNGKLSIML-QTIYLLHL 182

  Fly   184 KPFECHRNGQLLPINEGQFCAGNRDRSFCRSNSGSPLTADFTY-GVKNITVQVGLVSYGSELCSP 247
            |..||.|... ..:|..|.|||.::...||.:||.||:.:..: ..|:..||:|:||:|...|..
  Fly   183 KRNECKRKLN-FNLNSRQICAGTKNGDTCRGDSGGPLSTNILFPSNKSYEVQLGIVSFGDPECRG 246

  Fly   248 TSVYTDVVAFKDWIYNTVRNFE------TKGD------------------------QVVYEECRS 282
            ..|||||.::.|||.:|:...:      :.||                        .::|..|
  Fly   247 VGVYTDVTSYVDWISSTIARNDYLPIGVSGGDIAMGNPIAPDANRHWTPAASPPLPSMLYNSC-- 309

  Fly   283 NWAEDVLVRLWEVSLH-QNTFS-GVLITNRFVLTVASAFPNIPLVMKVETKYLKSF--------- 336
              ::|:...:.::.:: ..::: |||||::.::..|:..|.:       ..||..|
  Fly   310 --SQDIAAPIAQLRIYWPGSYAVGVLITDQLIIAAATDLPTV-------AAYLYVFVVLEGISAI 365

  Fly   337 -DVESIHTHPRFTHSSMDNNIALLKLAHDVPNSDLVKPICIVPSPKLPRMLTTLVDETTNDFRGV 400
             .:||:..||.||.:...|:||:|||...: :|..:|||||        :.|.:..:.....|.:
  Fly   366 NQIESVSKHPNFTTNDYRNDIAVLKLVRSI-SSTAMKPICI--------LTTQIYQQNAEKAREL 421

  Fly   401 RNVTLNAINHI--------ECARRIGKPLKSNQFCVAQPIDFK--VQAPGSIIGTYRNIGDGNRY 455
            :.:..:.....        :||:.:|..:..||.|:..|.|..  .|....|:....|.....||
  Fly   422 KIIDTDLAEQFDVRLMEGSQCAKHLGFQINENQVCMVDPSDTSNPRQKRSYIVVGGMNANGQIRY 486

  Fly   456 YLFGLMSYSKDGMVVYTYIQSYLDWIMDKVY 486
            .|.|:.|:|...::|:|.:..:.|||:..:|
  Fly   487 ILVGIFSFSSKNILVFTNVMRHTDWILSLLY 517

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33465	NP_001033950.2	Tryp_SPc	46..264	CDD:238113	78/223 (35%)
		Tryp_SPc	46..261	CDD:214473	76/220 (35%)
		Tryp_SPc	293..484	CDD:304450	52/212 (25%)
		Tryp_SPc	293..481	CDD:214473	50/209 (24%)
CG10764	NP_611213.2	Tryp_SPc	37..260	CDD:214473	79/236 (33%)
		Tryp_SPc	38..263	CDD:238113	80/238 (34%)
		Tryp_SPc	317..512	CDD:214473	50/210 (24%)
		Tryp_SPc	317..512	CDD:304450	50/210 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45463239
Domainoid	1	1.000	102	1.000	Domainoid score	I4289
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	139	1.000	Inparanoid score	I4489
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000404
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.990