DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33465 and Prss48

DIOPT Version :9

Sequence 1:	NP_001033950.2	Gene:	CG33465 / 3885587	FlyBaseID:	FBgn0053465	Length:	488	Species:	Drosophila melanogaster
Sequence 2:	NP_001001650.1	Gene:	Prss48 / 368202	MGIID:	2685865	Length:	312	Species:	Mus musculus

Alignment Length:	284	Identity:	85/284 - (29%)
Similarity:	124/284 - (43%)	Gaps:	44/284 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 RVLSLALIGLVLCQG---LAQLLDKKCHDP-KTSENINFNHGATETAPWMASIYKNNQFICDGTL 63
            :||.|..:|..  ||   ..:.|...|..| .|...:.....|....||..|:..:....|.|:|
Mouse     7 KVLLLLFLGAF--QGSFTKKKNLQSVCGRPVHTGRIVGGQDAALGRWPWQVSLRFDYTHSCGGSL 69

  Fly    64 VHKLFVLTAASCISKD--SQLY-VLFGMYNQYRDASQFFNNEQYGVAVAL----QHSNFRPNNGV 121
            :...:|||||.||.|.  |.|| |..|..::...::   ..|.|...:|:    :|:.
Mouse    70 ISDHWVLTAAHCIKKTWYSFLYSVWLGSIDREYSST---GKEYYVSRIAIPDKHRHTE------- 124

  Fly   122 NDIGLLRLYGEVTHYAHIRPICIILDHVVK--SAPFERF-EGFGWQQQGTEASSQVRQTVYLSQK 183
            .||.||:|...||..:.|.|||  |.::.|  :.|...: .|:|..|:|...|:.....|.:...
Mouse   125 ADIALLKLSSRVTFSSVILPIC--LPNISKQLTVPASCWVTGWGQNQEGHYPSTLQELEVPVISS 187

  Fly   184 KPFECHRN--GQLLP-----INEGQFCAGNRD--RSFCRSNSGSPLTADFTYGVKNITVQVGLVS 239
            :..|...|  |..||     |.|..||||.|.  :..|:.:||.||:.... ||..:   :|:||
Mouse   188 EACEQLYNPIGVFLPDLERVIKEDMFCAGERQSRKDSCKGDSGGPLSCHID-GVWRL---MGVVS 248

  Fly   240 YGSELCSP--TSVYTDVVAFKDWI 261
            :|.| |..  ..|||:|..::.||
Mouse   249 WGLE-CGKDLPGVYTNVTYYQKWI 271

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33465	NP_001033950.2	Tryp_SPc	46..264	CDD:238113	74/237 (31%)
		Tryp_SPc	46..261	CDD:214473	72/235 (31%)
		Tryp_SPc	293..484	CDD:304450
		Tryp_SPc	293..481	CDD:214473
Prss48	NP_001001650.1	Tryp_SPc	39..271	CDD:214473	73/248 (29%)
Prss48	NP_001001650.1	Tryp_SPc	40..274	CDD:238113	75/249 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910