DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33465 and CG12133

DIOPT Version :9

Sequence 1:	NP_001033950.2	Gene:	CG33465 / 3885587	FlyBaseID:	FBgn0053465	Length:	488	Species:	Drosophila melanogaster
Sequence 2:	NP_610540.2	Gene:	CG12133 / 36036	FlyBaseID:	FBgn0033469	Length:	340	Species:	Drosophila melanogaster

Alignment Length:	285	Identity:	76/285 - (26%)
Similarity:	118/285 - (41%)	Gaps:	36/285 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 PKTSENINFNHGATETAPWMASI----YKNNQF---ICDGTLVHKLFVLTAASCISKDSQLYVL- 85
            |.:|..:......:...||...:    |...|.   :|.|:|:...:|||||.|::. :..||.
  Fly    57 PPSSYIVGGMEAQSNQFPWTVLLGYEAYTAKQRPSPMCAGSLIASRYVLTAAHCLNV-NDFYVAR 120

  Fly    86 --FGMYNQYRD--------ASQFFNNEQYGVAVALQ--HSNFRPNNG--VNDIGLLRLYGEVTHY 136
              .|.::...|        .::.:......:.|.|:  |..:...||  .|||.||||...|.:.
  Fly   121 VRLGEHDTENDPDYTWLPNGAKIWAPAHVDIDVDLRVPHEQYYTRNGRHYNDIALLRLKSRVKYT 185

  Fly   137 AHIRPICIILDHVVKSAPFER--FEGFGWQQQGTEASSQVRQTVYLSQKKPFEC-HRNGQLLPIN 198
            ..||||||.....:.::.|:.  |:..||...|.:..|.|.:...:|...|.|| :|...||...
  Fly   186 LQIRPICIWPGIELSTSSFKNFPFQIAGWGDSGLQQKSTVLRQGTISGMSPDECLNRYPTLLVDK 250

  Fly   199 EGQFCAGNRDRSFC-RSNSGSPLTADFTYGVKNITVQVGLVSYGSELCSPTS------VYTDVVA 256
            :.|.||...|.:.. ..:|||||.|....|........|:.|||.   .|:|      |||...:
  Fly   251 DIQICAMGWDGTDTGLGDSGSPLMASVGRGADQFYYLAGITSYGG---GPSSYGYGPAVYTKTSS 312

  Fly   257 FKDWIYNTVRNFETKGDQVVYEECR 281
            :.:||...:.:......::.|:..|
  Fly   313 YYEWIKKKINDIAEDERKMKYKSVR 337

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33465	NP_001033950.2	Tryp_SPc	46..264	CDD:238113	72/249 (29%)
		Tryp_SPc	46..261	CDD:214473	70/246 (28%)
		Tryp_SPc	293..484	CDD:304450
		Tryp_SPc	293..481	CDD:214473
CG12133	NP_610540.2	Tryp_SPc	62..320	CDD:238113	72/261 (28%)
CG12133	NP_610540.2	Tryp_SPc	62..317	CDD:214473	70/258 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45463660
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940