DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG33465 and CG4650

DIOPT Version :9

Sequence 1:	NP_001033950.2	Gene:	CG33465 / 3885587	FlyBaseID:	FBgn0053465	Length:	488	Species:	Drosophila melanogaster
Sequence 2:	NP_609722.2	Gene:	CG4650 / 34859	FlyBaseID:	FBgn0032549	Length:	299	Species:	Drosophila melanogaster

Alignment Length:	276	Identity:	80/276 - (28%)
Similarity:	126/276 - (45%)	Gaps:	35/276 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 ALIGLVLCQGLAQLLDKKC---HDPKTSENINFNHGATETAPWMASIYKNN-QFICDGTLVHKLF 68
            ||:.|:...|.:|.||.:|   .:.|.:.||        ::||||.::.:. .::|.||::.:..
  Fly    10 ALLFLLPVPGSSQYLDGRCGLLTNGKIANNI--------SSPWMAYLHTSELLYVCGGTVITEKL 66

  Fly    69 VLTAASCISKDSQLYVLFGMYNQYRDASQFFNNEQYGVAVALQHSNFRPNNGVNDIGLLRLYGEV 133
            |||||.|.....||....|.:....||:....:| |.|:....||.:......|||.:|.|..::
  Fly    67 VLTAAHCTRASEQLVARIGEFIGTDDANDTMLSE-YQVSQTFIHSLYNTTTSANDIAILGLATDI 130

  Fly   134 THYAHIRPICII--------LDHVVKSAPFERFEGFGWQQQGTEASSQVRQTVYLSQKKPFECHR 190
            .....||||||:        :|::      :...|..|........|...:...:.::....|..
  Fly   131 VFSKTIRPICIVWWTIWRKYIDNI------QVLSGAQWGLPNDRNESDAFRITDIRRQPANMCST 189

  Fly   191 -NGQLLPINEGQFCAGNRDRSFCRSNSGSPLTADFTYGVKNIT--VQVGLVSYGSELCSPTSVYT 252
             ||  ..|...|||||:.|...|..:..|||.|..|:  |||.  |.:|:.: .::.|...||||
  Fly   190 LNG--TAILSSQFCAGDSDSKLCNVDFSSPLGAIITF--KNIQRYVLIGIAT-TNQKCKRASVYT 249

  Fly   253 DVVAFKDWIYNTVRNF 268
            ||::..|:|.:..|.:
  Fly   250 DVLSHTDFILSVWRQY 265

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33465	NP_001033950.2	Tryp_SPc	46..264	CDD:238113	68/229 (30%)
		Tryp_SPc	46..261	CDD:214473	67/226 (30%)
		Tryp_SPc	293..484	CDD:304450
		Tryp_SPc	293..481	CDD:214473
CG4650	NP_609722.2	Tryp_SPc	33..258	CDD:214473	70/244 (29%)
CG4650	NP_609722.2	Tryp_SPc	33..258	CDD:304450	70/244 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45463439
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000404
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_108863
Panther	1	1.100	-	-	P	PTHR24260
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.840