Protein Alignment CG33465 and PRSS53

DIOPT Version :9

• Sequence 1: NP_001033950.2
• Gene: CG33465 / 3885587
• FlyBaseID: FBgn0053465
• Length: 488
• Species: Drosophila melanogaster
• Sequence 2: XP_011544118.1
• Gene: PRSS53 / 339105
• HGNCID: 34407
• Length: 623
• Species: Homo sapiens
• Alignment Length: 490
• Identity: 112/490 - (22%)
• Similarity: 165/490 - (33%)
• Gaps: 166/490 - (33%)

  Fly    13 VLCQGLAQLLDKKCHD-----PKTSENINFNHGATETA--PWMASIYKNNQFICDGTLVHKLFVL 70
            ||.:|| |...:.|..     ||..|      |.|...  ||.||:.:....||.|:||...:||
Human    16 VLMEGL-QAAQRACGQRGPGPPKPQE------GNTVPGEWPWQASVRRQGAHICSGSLVADTWVL 73

  Fly    71 TAASCISK------DSQLYVLFGMYNQYRDASQFFNNEQYGVAVALQ----HSNFRPNNGVNDIG 125
            |||.|..|      :|...||..:..:......    |:.||| |||    ::::...   :|:.
Human    74 TAAHCFEKAAATELNSWSVVLGSLQREGLSPGA----EEVGVA-ALQLPRAYNHYSQG---SDLA 130

  Fly   126 LLRLYGEVTHYAHIRPICIILDHVVKSAPFERFE------GFGWQQQGTEASSQVR--------- 175
            ||:|....||    .|:|:       ..|..||.      ..||.|..::.....|
Human   131 LLQLAHPTTH----TPLCL-------PQPAHRFPFGASCWATGWDQDTSDGKCWPRLKLGEALCL 184

  Fly   176 ---------------------QT------------------VYLSQKKPFEC-----HRNGQLLP 196
                                 ||                  :.|..:....|     |:.....|
Human   185 PSVTVSAPNCPGFQSPLLPRSQTLAPAPSLSPAPGTLRNLRLRLISRPTCNCIYNQLHQRHLSNP 249

  Fly   197 INEGQFCAGNRD--RSFCRSNSGSP---LTADFTYGVKNITVQVGLVSYGSELCSPTS--VYTDV 254
            ...|..|.|.:.  :..|:.:||.|   |..|..:      ||.|::|:.|......:  :.|:.
Human   250 ARPGMLCGGPQPGVQGPCQGDSGGPVLCLEPDGHW------VQAGIISFASSCAQEDAPVLLTNT 308

  Fly   255 VAFKDWIYNTVR------------------------NFETKGDQVVYEECRSNWAEDVLVRLWEV 295
            .|...|:...|:                        :..|.|.|.   ...|.|.       ||.
Human   309 AAHSSWLQARVQGAAFLAQSPETPEMSDEDSCVACGSLRTAGPQA---GAPSPWP-------WEA 363

  Fly   296 SL-HQNTFS--GVLITNRFVLTVASAF-----P---NIPLVMKVETKYLKSFDVESIHTHPRFTH 349
            .| ||...:  |.|::...|||.|..|     |   ::.|..:.|...||...:...:|||...:
Human   364 RLMHQGQLACGGALVSEEAVLTAAHCFIGRQAPEEWSVGLGTRPEEWGLKQLILHGAYTHPEGGY 428

  Fly   350 SSMDNNIALLKLAHDVPNSDLVKPICI-VPSPKLP 383
                 ::|||.||..|.....::|:|: .|...||
Human   429 -----DMALLLLAQPVTLGASLRPLCLPYPDHHLP 458

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33465	NP_001033950.2	Tryp_SPc	46..264	CDD:238113	64/293 (22%)
		Tryp_SPc	46..261	CDD:214473	63/290 (22%)
		Tryp_SPc	293..484	CDD:304450	31/103 (30%)
		Tryp_SPc	293..481	CDD:214473	31/103 (30%)
PRSS53	XP_011544118.1	Tryp_SPc	42..316	CDD:238113	65/298 (22%)
		Tryp_SPc	43..314	CDD:214473	64/295 (22%)
		Tryp_SPc	359..>512	CDD:304450	32/112 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910