DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33465 and plg

DIOPT Version :9

Sequence 1:	NP_001033950.2	Gene:	CG33465 / 3885587	FlyBaseID:	FBgn0053465	Length:	488	Species:	Drosophila melanogaster
Sequence 2:	NP_958880.2	Gene:	plg / 322691	ZFINID:	ZDB-GENE-030131-1411	Length:	818	Species:	Danio rerio

Alignment Length:	281	Identity:	68/281 - (24%)
Similarity:	112/281 - (39%)	Gaps:	63/281 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 CQGLAQLLDKKCHDPKTSENINFNH------GATETAPWMASIYKNNQF-ICDGTLVHKLFVLTA 72
            |:.|      ||..|.|.....|..      ....:.||..|:....:. .|.|||:...:|:||
Zfish   570 CESL------KCGQPATKPKRCFGRIVGGCVSKPHSWPWQISLRTRGKIHFCGGTLIDPQWVVTA 628

  Fly    73 ASCISKD---SQLYVLFGMY--------NQYRDASQFFNNEQYGVAVALQHSNFRPNNGVNDIGL 126
            |.|:.:.   |...::.|::        .|.||.::.....                 ...||.|
Zfish   629 AHCLERSDSPSAYKIMLGIHTERATESSKQERDVTKIIKGP-----------------AGTDIAL 676

  Fly   127 LRLYGEVTHYAHIRPICI-ILDHVVKSAPFERFEGFGWQQQGTEASSQVRQTVY-LSQKKPFECH 189
            |:|.........:.|:|: ..|::|.|.......|:| :.|.|.....:::|.: :.:.|  .|:
Zfish   677 LKLDRPALINDKVSPVCLPEKDYIVPSNTECYVTGWG-ETQDTGGEGYLKETGFPVIENK--VCN 738

  Fly   190 R----NGQLLPINEGQFCAGNRD--RSFCRSNSGSPLTADFTYGVKNITVQVGLVSYG---SELC 245
            |    ||:   :.:.:.||||.:  ...|:.:||.||..   | .:|..|..|:.|:|   :...
Zfish   739 RPSFLNGR---VKDHEMCAGNIEGGNDSCQGDSGGPLVC---Y-AQNTFVLQGVTSWGLGCANAM 796

  Fly   246 SPTSVYTDVVAFKDWIYNTVR 266
            .| .|||.|..|.|||..:::
Zfish   797 KP-GVYTRVSKFVDWIERSIK 816

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33465	NP_001033950.2	Tryp_SPc	46..264	CDD:238113	61/240 (25%)
		Tryp_SPc	46..261	CDD:214473	59/237 (25%)
		Tryp_SPc	293..484	CDD:304450
		Tryp_SPc	293..481	CDD:214473
plg	NP_958880.2	PAN_AP_HGF	31..104	CDD:238532
		KR	109..190	CDD:214527
		KR	190..270	CDD:214527
		KR	281..361	CDD:214527
		Kringle	376..453	CDD:306546
		KR	490..572	CDD:214527	1/1 (100%)
		Tryp_SPc	589..813	CDD:238113	61/251 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910