DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33465 and GZMM

DIOPT Version :9

Sequence 1:	NP_001033950.2	Gene:	CG33465 / 3885587	FlyBaseID:	FBgn0053465	Length:	488	Species:	Drosophila melanogaster
Sequence 2:	NP_005308.2	Gene:	GZMM / 3004	HGNCID:	4712	Length:	257	Species:	Homo sapiens

Alignment Length:	228	Identity:	66/228 - (28%)
Similarity:	108/228 - (47%)	Gaps:	28/228 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 PWMASIYKNNQFICDGTLVHKLFVLTAASCIS-KDSQLYVLFGMYNQYRDASQFFNNEQYGVAVA 109
            |:|||:.:|...:|.|.|||..:|||||.|:: :.:||.::.|::........|.      :..|
Human    38 PYMASLQRNGSHLCGGVLVHPKWVLTAAHCLAQRMAQLRLVLGLHTLDSPGLTFH------IKAA 96

  Fly   110 LQHSNFRPNNGV-NDIGLLRLYGEVTHYAHIRPICIILDHVVKSAPFE-RFEGFGWQQQGTEASS 172
            :||..::|...: ||:.||:|.|:|.....|||:.:.....|.:|... ...|:|...||...|.
Human    97 IQHPRYKPVPALENDLALLQLDGKVKPSRTIRPLALPSKRQVVAAGTRCSMAGWGLTHQGGRLSR 161

  Fly   173 QVRQTVYLSQKKPFECHR----NGQLLPINEGQFC--AGNRDRSFCRSNSGSPLTADFTYGVKNI 231
            .:|: :.|.......|:.    ||.|.|   ...|  |.::|::.|:.:||.||..    |...:
Human   162 VLRE-LDLQVLDTRMCNNSRFWNGSLSP---SMVCLAADSKDQAPCKGDSGGPLVC----GKGRV 218

  Fly   232 TVQVGLVSYGSELCS---PTSVYTDVVAFKDWI 261
            ..:|  :|:.|.:|:   ...|.|.|..:..||
Human   219 LARV--LSFSSRVCTDIFKPPVATAVAPYVSWI 249

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33465	NP_001033950.2	Tryp_SPc	46..264	CDD:238113	66/228 (29%)
		Tryp_SPc	46..261	CDD:214473	64/226 (28%)
		Tryp_SPc	293..484	CDD:304450
		Tryp_SPc	293..481	CDD:214473
GZMM	NP_005308.2	Tryp_SPc	26..252	CDD:238113	66/228 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910