DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33465 and CG18636

DIOPT Version :9

Sequence 1:	NP_001033950.2	Gene:	CG33465 / 3885587	FlyBaseID:	FBgn0053465	Length:	488	Species:	Drosophila melanogaster
Sequence 2:	NP_995714.2	Gene:	CG18636 / 2768923	FlyBaseID:	FBgn0032551	Length:	349	Species:	Drosophila melanogaster

Alignment Length:	292	Identity:	91/292 - (31%)
Similarity:	140/292 - (47%)	Gaps:	41/292 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 ALIGL-----------VLCQGLAQLLDKKC---HDPKTSENINFNHGAT-ETAPWMASIYK-NNQ 56
            ||||:           :|..|.:|.||..|   ...:|:..|...|.|. .::|||..::. .:.
  Fly     4 ALIGVPTFVGIILMFQLLHSGCSQFLDPACGIRTQSRTAYRIINGHTAKYNSSPWMVFLHSTTDM 68

  Fly    57 FICDGTLVHKLFVLTAASCISKDSQLYVLFGMYNQYR--DASQFFNN--EQYGVAVALQHSNFRP 117
            |:|.|:|:....|||||.|...:..|....|.|.:.|  :.:.::.|  |::.|....:|..:.|
  Fly    69 FVCGGSLITDKLVLTAAHCFIANQHLVARLGEYERTRSEECTGYYCNFREEHMVDAGFKHKLYDP 133

  Fly   118 NNGVNDIGLLRLYGEVTHYAHIRPICIILDHVVKSAPFERFEGF----------GWQQQGTEASS 172
            |...|||.:|||...|.:..:|||||::.||        |:..:          ||.:...|:.|
  Fly   134 NTHANDIAILRLSKSVVYRDNIRPICVVWDH--------RWRHYLDKIDLLTATGWGKTQMESDS 190

  Fly   173 QVRQTVYLSQKKPFECHR-NGQLLPINEGQFCAGNRDRSFCRSNSGSPLTADFTYGVKNITVQVG 236
            ...||:.:.::.|..|.: .||.:..|  ||||||.|.:.|..:||.||.|..|:......||||
  Fly   191 DALQTLDIRRQPPDVCAKFIGQTIAGN--QFCAGNWDSNLCNGDSGGPLGAVITHKNTQRFVQVG 253

  Fly   237 LVSYGSELCSPTSVYTDVVAFKDWIYNTVRNF 268
            :.||.:..|...||:|||::..::|....|.:
  Fly   254 IASYTNRNCQKASVFTDVLSHAEFILRVWRMY 285

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33465	NP_001033950.2	Tryp_SPc	46..264	CDD:238113	76/233 (33%)
		Tryp_SPc	46..261	CDD:214473	75/230 (33%)
		Tryp_SPc	293..484	CDD:304450
		Tryp_SPc	293..481	CDD:214473
CG18636	NP_995714.2	Tryp_SPc	44..278	CDD:214473	78/243 (32%)
CG18636	NP_995714.2	Tryp_SPc	45..278	CDD:238113	78/242 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45463390
Domainoid	1	1.000	102	1.000	Domainoid score	I4289
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	108	1.000	Inparanoid score	I3480
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000404
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_108863
Panther	1	1.100	-	-	P	PTHR24260
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.890